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Teams looking for a bounce-back season meet when the Los Angeles Angels face the Boston Red Sox in a Patriots' Day matchup at Fenway Park in Boston. The Angels (7-8), who have not had a winning season since 2015, finished third in the American League West in 2022, going 73-89. The Red Sox (8-8), who have made the postseason in five of the past 10 seasons, including two World Series titles, finished fifth in the AL East at 78-84 a year ago. Shohei Ohtani will start for the Angles, while Brayan Bello takes the hill for Boston. 

First pitch is set for 11:10 a.m. ET. Los Angeles is a -140 favorite on the money line (risk $140 to win $100) in the latest Angels vs. Red Sox odds from Caesars Sportsbook, while the total number of runs Vegas thinks will be scored, or the over/under, is 8. Before making any Red Sox vs. Angels picks, be sure to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons, and it finished the 2022 MLB season on a 20-14 roll. Anybody who has followed it has seen profitable returns.

Now, the model has dialed in on Red Sox vs. Angels and revealed its predictions and best bets. You can visit SportsLine now to see the model's MLB picks. Here are the MLB odds and betting trends for Angels vs. Red Sox:

  • Red Sox vs. Angels money line: Angels -140, Red Sox +118
  • Red Sox vs. Angeles over/under: 8 runs
  • Red Sox vs. Angels run line: Angels -1.5 (+115)
  • LAA: The Angels are 6-1 in their last seven when their opponent scores two runs or less in their previous game
  • BOS: The Red Sox are 4-1 in their last five games following a win
  • Red Sox vs. Angels picks: See picks at SportsLine

Why you should back the Red Sox

Rafael Devers is off to a solid start to the season, hitting .262 with seven homers, 15 RBI and 14 runs scored. In Saturday's 9-7 win over the Angels, Devers homered and drove in a pair of runs. He has had five multi-hit games already this season, including a 3-for-5 performance with a double in a 9-8 win over Baltimore on April 1. He has feasted on Angels pitching throughout his career. In 25 games against them, he is hitting .295 with four doubles, nine homers and 21 RBI.

Justin Turner has been red hot of late. He has hit safely in six consecutive games, including back-to-back 2-for-4 performances at Tampa Bay on Tuesday and Wednesday. He was 2-for-4 with a homer and two RBI on Sunday. In 33 career games against the Angels, he is hitting .254 with three doubles, three homers and 13 RBI. For the season, he is hitting .271 with four doubles, six RBI and nine runs scored. See who to back at SportsLine.

Why you should back the Angels

Los Angeles will counter with right-hander Shohei Ohtani (2-0, 0.47 ERA). In three starts this season, he has allowed just one earned run. Ohtani has won each of his last two starts, including a 2-0 victory over Washington on Tuesday. In that game, he pitched seven innings and allowed just one hit, five walks and struck out six. In four career starts against Boston, he is 3-1 with a 2.35 ERA. In 23 innings, he has allowed six earned runs on 19 hits with four walks and 22 strikeouts.

Helping power the Angels offense is right fielder Hunter Renfroe. He has five multi-hit games this season, including a 3-for-5 performance in a 12-11 loss to Toronto on April 9. In that game, he doubled, homered and drove in four runs. For the season, Renfroe is hitting .268 with three homers, 11 RBI and nine runs scored. In 13 career games against Boston, he is hitting .286 with five doubles, five homers and 14 RBI. See who to back at SportsLine.

How to make Angels vs. Red Sox picks

SportsLine's model is leaning Over on the run total, as the simulations have the teams combining for 9.3 runs. It also says one side of the money line has all the value. You can only get the model's pick at SportsLine.

So who wins Red Sox vs. Angels? And which side of the money line has all the value? Visit SportsLine now to see which side of the money line to jump on, all from the advanced model that finished last season on a 20-14 roll on money-line picks, and find out.