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The Cleveland Cavaliers and the Detroit Pistons are set to square off in a Central Division matchup at 6 p.m. ET on Sunday at Little Caesars Arena. Detroit is 11-37 overall and 7-15 at home, while the Cavaliers are 30-19 overall and 15-10 on the road. Cleveland has dominated this series in recent years, winning five of its last six meetings against Detroit. 

Cleveland is favored by 7.5-points in the latest Pistons vs. Cavaliers odds from Caesars Sportsbook, and the over-under is set at 207.5. Before entering any Cavaliers vs. Pistons picks, you'll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model enters Week 15 of the 2021-22 NBA season on a stunning 58-32 roll on all top-rated NBA picks, returning over $2,100. Anyone following it has seen huge returns.

Now, the model has set its sights on Pistons vs. Cavaliers. You can head to SportsLine to see its picks. Here are several NBA betting lines for Pistons vs. Cavaliers:

  • Pistons vs. Cavaliers spread: Pistons +7.5
  • Pistons vs. Cavaliers over-under: 207.5 points
Featured Game | Detroit Pistons vs. Cleveland Cavaliers

What you need to know about the Pistons

Detroit received a tough blow this past Friday as the Pistons fell 119-103 to the Orlando Magic. Shooting guard Cade Cunningham had a pretty forgettable game, playing for 30 minutes but putting up just eight points on 3-for-17 shooting. The rookie enters Sunday's showdown averaging 16.0 points, 5.4 rebounds and 5.2 assists per game. 

The Pistons have lost six of their last seven games, but they're 5-1 against the spread in their last six games at home. In addition, Detroit is 4-1 against the spread in its last five games played in January. 

What you need to know about the Cavaliers

Meanwhile, the Cavaliers had enough points to win and then some against the Milwaukee Bucks this past Wednesday, taking their contest 115-99. Cleveland got the victory on the backs of several key players, and it was point guard Darius Garland out in front picking up 19 points and eight assists. For the season, Garland is averaging 19.7 points, 8.2 assists and 3.3 rebounds per game. 

The Cavaliers are giving up just 102.2 points per game this season, the second-best mark in the NBA. Offensively, Cleveland is averaging 107.1 points per contest, which ranks 23rd in the league. 

How to make Pistons vs. Cavaliers picks

The model has simulated Pistons vs. Cavaliers 10,000 times and the results are in. We can tell you that the model is leaning under, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Cavaliers vs. Pistons? And which side of the spread hits well over 50 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its NBA picks.