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An Eastern Conference bout features the New York Knicks (18-14) and the Chicago Bulls (13-18) squaring off on Friday night. This will be the third matchup of the year between these two teams, and New York won back-to-back games in Chicago just last week. The Knicks have a 7-8-1 home record against the spread in 2022, while Chicago has gone 8-8-1 on the road ATS. Alex Caruso (concussion) is out for the Bulls, while Quentin Grimes (ankle) is questionable for New York.

Tip-off is scheduled for 7:30 p.m. ET from Madison Square Garden. Caesars Sportsbook lists the Knicks as a 5.5-point favorite in the latest Bulls vs. Knicks odds. The over/under for total points is set at 225.5. Before making any Knicks vs. Bulls picks, be sure to see the NBA predictions and betting advice from SportsLine's proven model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past four-plus seasons. The model enters Week 10 of the 2022-23 NBA season on a stunning 28-12 roll on all top-rated NBA picks this season, returning almost $1,400. Anyone following it has seen huge returns.

Now, the model has set its sights on Bulls vs. Knicks and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and betting lines for Knicks vs. Bulls:

  • Bulls vs. Knicks spread: New York -5.5
  • Bulls vs. Knicks Over-Under: 225.5 points
  • Bulls vs. Knicks money line: New York -225, Chicago +185
  • NYK: Knicks are 6-0 ATS in their last six games playing on one day of rest
  • CHI: Over is 5-1 in the Bulls' last six games following an ATS win
  • Bulls vs. Knicks picks: See picks at SportsLine

Why the Knicks can cover

Forward Julius Randle is a powerful presence who attacks downhill and is an exceptional rebounder. The Kentucky product owns good footwork to get position offensively, and he can score in the post or from the perimeter. Randle is averaging 22.5 points and 9.3 rebounds per game. In his last game, he dropped 30 points, 13 rebounds, and four assists.

Guard Immanuel Quickley is a superb scoring threat off the bench. Quickley thrives as an off-ball shooter with an effortless stroke from downtown. The 2020 first-round pick can create his own shot with a quick release and has the strength to absorb contact down low. Quickley logs 10.3 points, 4.0 rebounds, and 2.9 assists, and on Dec. 20, he racked up 22 points, four rebounds, and went 5-of-6 from beyond the arc. 

Why the Bulls can cover

Forward DeMar DeRozan is an elite scorer who excels in the mid-range. DeRozan has an array of moves to get past his man with the ability to finish with force in the paint. The five-time All-Star has a knack for drawing contact and getting to the line, and he is shooting 88% from the free-throw line on 8.1 attempts per game. Additionally, he's leading the team in scoring (25.9) with 5.0 rebounds and 4.7 assists per game.

Center Nikola Vucevic provides Chicago with a top-tier rebounder. Vucevic is relentless on the boards and uses his size as leverage to box out defenders. The USC product also can score from anywhere on the court as Vucevic has a reliable jumper with a soft touch around the basket. The 32-year-old averages 16.8 points and 10.4 rebounds, and he has scored 20-plus points in three straight games.

How to make Bulls vs. Knicks picks

SportsLine's model is leaning Over on the total, projecting the teams to combine for 232 points. The model also says one side hits in over 50% of simulations. You can only get the pick at SportsLine.

So who wins Knicks vs. Bulls? And which side hits over 50% of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its NBA picks, and find out.