With 116 rushing yards last week, Jonathan Taylor is now tied atop the rushing leaderboard as both he and the injured Derrick Henry have 937 yards. Taylor has been the catalyst for the Indianapolis Colts (5-5) this season as Indy is 5-0 when he rushes for over 100 yards but 0-5 when he fails to reach the century mark. His Colts will visit the Buffalo Bills (6-3) on Sunday with Buffalo possessing the league's No. 3 rushing defense both in terms of yards and yards per attempt. The Bills have only allowed one 100-yard rusher all season and it was, coincidentally, Henry in Week 6. You may be able to stream the game on Paramount+.

This 1 p.m. ET kickoff will take place from Highmark Stadium in Orchard Park, N.Y. Caesars Sportsbook has Buffalo as seven-point favorites in the latest Colts vs. Bills odds. The over-under is 49.5 after fluctuating between 49 and 50 during the week. In select markets, Sunday's matchup can be seen live on CBS and streamed live on Paramount+ with their must-have Premium plan.

Paramount+ now has levels of membership so you can watch your local NFL on CBS matchups and much more. The Premium Plan is $9.99 per month and you can watch your local CBS live stream, including plenty of sports like SEC on CBS, NFL on CBS, and the PGA Tour, with no ads, on demand and the ability to download episodes for offline viewing. Both plans come with a free week to start and include the NFL on CBS, so sign up now here.

How to watch Colts vs. Bills

  • Date: Sunday, Nov. 21
  • Time: 1 p.m. ET
  • TV: CBS 
  • Streaming: Paramount+

Week 11 NFL picks for Bills vs. Colts

Before you tune in to Sunday's Colts vs. Bills game, you need to see the NFL picks from SportsLine's advanced computer model. The model, which simulates every NFL game 10,000 times, is up almost $7,500 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 11 of the 2021 season on an incredible 128-89 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

For Bills vs. Colts, the model is backing the Buffalo as seven-point home favorites. The 5-5 record of the Colts is fitting because they only beat the bad teams while they can't contend with the good teams. The combined record of the teams Indy has beaten is 12-34 (.260 W-L%), while the combined record of the teams it has lost to is 24-14 (.632 W-L%). At 6-3, Buffalo has a .667 W-L%.

The Bills' pass defense is historically good and will make this game one-dimensional for the Colts offense. Buffalo is limiting opposing QBs to a 60.7 passer rating which would be the lowest by any team in a dozen years. The defense has also allowed the fewest passing TDs, allowed the lowest completion percentage and has the most interceptions in the league. It has to be salivating at a QB like Carson Wentz who threw an ill-fated, left-handed pick-six from his own endzone in Week 8.

The model has Wentz having at least one giveaway on Sunday and being held to barely 200 yards through the air. That will allow Buffalo to focus its efforts on slowing down Taylor, who is projected to have his lowest scrimmage yardage game since Week 3. With the Colts offense stifled, Buffalo (-7) is projected to win by 10 points and cover well over 50 percent of the time.

How to watch, live stream the NFL on CBS

Now that you know what to pick, get ready to watch your live local NFL on CBS games on Paramount+ on any device you want. Visit Paramount+ now to stream your live local CBS sporting events, including the NFL, SEC on CBS, and so much more