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Of the 16 games on the Week 1 NFL schedule, only one has a spread larger than a touchdown. That typically means it will be tough sledding for anyone making NFL office pool picks or NFL confidence pool picks. However, in an era where fans have access to every game, every week, making NFL pool picks with your friends, family and co-workers can help enhance your viewing experience significantly. Whether you're playing for cash, prizes or simply bragging rights, making NFL predictions can keep you emotionally invested in each game.

In Week 1, the Bills are 1.5-point road favorites over the Jets on Monday Night Football in the first Josh Allen vs. Aaron Rodgers matchup in the AFC East. Deciding that game correctly and getting off to a fast start in your NFL picks can help spurn you onto season-long success. If you're up for it, CBS Sports has the perfect game to keep you locked in all season long.

Compete for $100,000 or start a pool with friends

It's time to raise the stakes with CBS Sports Football Pick'em. Join the challenge to compete for the $100,000 jackpot and guaranteed cash prizes each week or start a customizable pool to compete against your friends. (No purchase necessary. See Terms and Rules for details.)

You can win the $100,000 jackpot each week for hitting the full slate and tiebreakers. Even if no one hits the jackpot, CBS Sports is giving away a guaranteed $1,000 to the winner each week. In addition, the player with the most correct picks at the end of the season gets $5,000.

If you're looking to start a pick'em pool with your friends, family or colleagues, group settings include a variety of games suitable for every fan, including straight-up picks, against-the-spread picks, survivor pools, confidence points and much more. You can play on your desktop or on the CBS Sports app, so sign up here today

Get football picks for every game from a proven NFL model

We'll give you one team to consider backing during the NFL's opening week. SportsLine's advanced computer model, which simulates every NFL game 10,000 times, is predicting the Denver Broncos to take care of business at home versus the Las Vegas Raiders.

New Broncos head coach Sean Payton has earned a reputation as a quarterback guru, winning a Super Bowl in New Orleans with Drew Brees and going 152-89 while winning seven division titles in 15 years with the Saints. Now, he'll look to revive Russell Wilson's career after a disappointing first year with the Broncos in 2022.

Javonte Williams is healthy and free-agency signings Samaje Perine and Mike McGlinchey should further bolster the Denver running game. Meanwhile, the model is expecting a new-look Raiders offense to struggle with Jimmy Garoppolo at the helm, predicting the offense barely produces 300 yards with Denver winning in well over 50% of simulations. Join a pool now to lock in your picks.

Make NFL pool picks at CBS Sports

Show your skills, beat your friends and coworkers, and take home guaranteed prize money. Create a pool, get your friends involved, and keep the competition going all season long