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Sam Darnold and the Carolina Panthers (4-8) hit the road to take on Geno Smith and the Seattle Seahawks (7-5) in a NFL Week 14 game on Sunday at Lumen Field. The Panthers are coming off a bye in Week 13, but beat the Denver Broncos 23-10 in their last outing. Meanwhile, Seattle is coming off a 27-23 win over the defending Super Bowl champion Los Angeles Rams. Carolina is 0-5 on the road, while Seattle is 3-2 at home. Both teams are 6-6 against the spread in 2022.

Kickoff is at 4:25 p.m. ET. Seattle is favored by 3.5 points in the latest Seahawks vs. Panthers odds from Caesars Sportsbook, and the over/under is set at 44.5. Before making any Panthers vs. Seahawks picks, you'll want to see the NFL predictions and betting advice from the proven computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 14 of the 2022 NFL season on an incredible 156-112 run on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Seahawks vs. Panthers and just locked in its picks and NFL predictions. You can head to SportsLine now to see the model's picks. Here are several NFL betting lines for Seahawks vs. Panthers:

  • Seahawks vs. Panthers spread: Seahawks -3.5
  • Seahawks vs. Panthers over/under: 44.5 points
  • Seahawks vs. Panthers money line: Seattle -205, Carolina +170
  • Seahawks vs. Panthers picks: See picks here

What you need to know about the Seahawks

Seattle's passing attack was lethal in the team's Week 13 win over the Rams. Smith completed 28 of 39 passes for 367 yards, three touchdowns and one interception for a quarterback rating of 116.1. His top two pass catchers were Tyler Lockett (9-128-1) and DK Metcalf (8-127-1).

Seattle has a lot on the line in the final month of the regular season. The Seahawks currently hold the final Wild Card spot in the NFC and trail the San Francisco 49ers by one game in the NFC West race. With games remaining against the 49ers, Chiefs and Jets, Seattle can't afford to slip up and lose at home this week to the Panthers.

What you need to know about the Panthers

Meanwhile, Carolina was able to grind out a solid victory over the Denver Broncos two weeks ago, winning 23-10. Carolina's success was spearheaded by the efforts of WR D.J. Moore, who caught four passes for 103 yards and one TD, and QB Sam Darnold, who passed for one TD and 164 yards in addition to punching in one rushing touchdown. Darnold ended up with a quarterback rating of 103.8.

The Panthers' offense showed some signs of life in Darnold's first start of the season against a very talented Denver defense. They will be facing a Seattle defense in Week 14 that has been struggling as of late -- particularly against the run. The Seahawks are the second-worst rushing defense in the NFL, allowing 155.3 yards per game on the ground, which could open the door for a big game from Carolina running backs D'Onta Foreman and Chuba Hubbard.

How to make Panthers vs. Seahawks picks

The model has simulated Seahawks vs. Panthers 10,000 times and the results are in. The model is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in more than 60% of simulations. You can only see the model's pick at SportsLine.

So who wins Seahawks vs. Panthers? And which team covers more than 60% of the time? Visit SportsLine now to see which side of the Panthers vs. Seahawks spread you should jump on, all from the advanced model that is on an incredible 156-112 run, and find out.