The No. 8 Kansas Jayhawks and the No. 13 Iowa State Cyclones are set to square off in a Big 12 matchup at noon ET on Saturday at James H. Hilton Coliseum. The Cyclones are 15-6 overall and 11-0 at home, while Kansas is 18-4 overall and 4-2 on the road. Kansas is 9-13 against the spread this season, while Iowa State has a 12-9 ATS mark. Kansas won the first matchup of the season between these teams 62-60 on Jan. 14.

The Jayhawks are favored by 1.5 points in the latest Iowa State vs. Kansas odds from Caesars Sportsbook, and the over/under is set at 135.5. Before entering any Kansas vs. Iowa State picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. The model enters Week 13 of the season 50-29 on all-top rated college basketball picks, returning more than $1,200 for $100 players. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Iowa State vs. Kansas. You can head to SportsLine to see its picks. Here are several college basketball odds for Kansas vs. Iowa State:

  • Iowa State vs. Kansas spread: Kansas -1.5
  • Iowa State vs. Kansas over/under: 135.5 points
  • Iowa State vs. Kansas money line: Iowa State +115, Kansas -135
  • Iowa State vs. Kansas picks: See picks here
Featured Game | Iowa State Cyclones vs. Kansas Jayhawks

What you need to know about Iowa State

Iowa State fell 80-77 to the Texas Tech Red Raiders on Monday. Guard Jaren Holmes had a tough game, picking up four fouls and turning the ball over four times en route to a 3-for-12, 9-point finish. The Cyclones are now just 2-4 in their last six games, but they also had wins over top-10 Kansas State and Texas squads during that span, so they can compete with anybody. 

The Cyclones use a balanced offensive attack that features four players who average 9.1 or more points per game. Holmes (13.5 ppg) and Gabe Kalscheur (13.4 ppg) lead the way. They are tough defensively, giving up just 61.4 points per game. 

What you need to know about Kansas

Meanwhile, the Jayhawks had a great showing against the Kansas State Wildcats on Tuesday, taking that Sunflower Showdown game 90-78. Kansas guard Kevin McCullar Jr. looked sharp as he posted a double-double on 16 points and 13 boards. That was the second straight win for the Jayhawks coming off a three-game losing streak, so they appear to be rounding back into the form they enjoyed during a fast start to this season.

The Jayhawks average 76.6 points per game with McCullar averaging 10.7 ppg. Jalen Wilson (21.3 ppg) and freshman Gradey Dick (14.5) are the top scoring options. 

How to make Iowa State vs. Kansas picks

The model has simulated Iowa State vs. Kansas 10,000 times and the results are in. The model is leaning Over on the total, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Kansas vs. Iowa State? And which side of the spread hits well over 50% of the time? Visit SportsLine now to find out, all from the model that has crushed its top-rated college basketball picks this year