A Big Ten showdown takes place when No. 18 Ohio State (16-7) hosts Indiana (16-9) on Monday evening. Both teams are looking to pick up a win in this conference battle. Indiana has lost four straight games, all against Big Ten foes. Ohio State was upset in its last game as Iowa topped the Buckeyes 75-62 on Saturday. 

Tipoff is at 7 p.m. ET from Value City Arena. Caesars Sportsbook lists the Buckeyes at -6.5 in the latest Ohio State vs. Indiana odds, while the over-under for total points is set at 135.5, up a point from the opening line. Before making any Indiana vs. Ohio State picks, be sure to check out the college basketball predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,000 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Ohio State vs. Indiana, and just locked in its picks and CBB predictions. You can visit SportsLine now to see the picks. Here are the college basketball odds and betting lines for Indiana vs. Ohio State:

  • Indiana vs. Ohio State spread: Buckeyes -6.5
  • Indiana vs. Ohio State over-under: 135.5 points
  • Indiana vs. Ohio State money line: Hoosiers +230, Buckeyes -280
  • OSU: Buckeyes are 5-1 ATS in their last six games following a straight-up loss
  • IND: Hoosiers are 8-3 ATS in their last 11 Monday games
Featured Game | Ohio State Buckeyes vs. Indiana Hoosiers

Why Ohio State can cover 

Junior forward E.J. Liddell is a staple for this Buckeyes team. Liddell is ranks fourth in the Big Ten in scoring (19.7), is tied for first in blocks (2.6) and averages 7.6 rebounds per game. The Illinois native has been one of the most efficient 3-point shooters in the conference as well. He ranks 11th in the Big Ten in 3-point percentage (.405). On Feb. 6 against Maryland, Liddell finished with 24 points, 11 rebounds and five assists.

Freshman guard Malaki Branham averages 11.2 points and 3.7 rebounds. He is a sniper for Ohio State, ranking second in the conference in 3-point percentage (.458). Branham has produced double-digit scoring outings in six of his last 10 games. In his last matchup, the Ohio native had 22 points, eight rebounds, and two steals.

Why Indiana can cover

The Hoosiers controlled the matchup and beat Ohio State 67-51 on Jan. 6. Junior forward Trayce Jackson-Davis led the way for Indiana. He finished with a team-high 27 points, 12 rebounds and five blocks. Redshirt senior forward Race Thompson added 11 points and seven rebounds.

The Hoosiers played stingy defense and forced Ohio State to shoot a measly 31 percent from the field and 30 percent from downtown. Indiana also dominated in the paint, outscoring the Buckeyes 38-10. This matchup showcased Indiana's ability to play commanding defense against a conference foe. The Hoosiers will look to sweep the season series and halt their four-game losing streak. 

How to make Indiana vs. Ohio State picks

SportsLine's model is leaning over on the total, projecting 140 combined points. It also says one side of the spread hits well over 60 percent of the time. You can only get the model's pick at SportsLine

So who wins Ohio State vs. Indiana? And which side of the spread hits well over 60 percent of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up almost $2,000 on its college basketball picks the last five-plus years, and find out.