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The Colorado State Rams ended their 2019 season with a thud, losing their final three games to finish with a 4-8 overall record and 3-5 mark in the Mountain West Conference. Their struggles have continued this year as they opened the 2020 campaign with a 38-17 setback at Fresno State. The Rams aim to end the slide when they host the conference-rival Wyoming Cowboys on Thursday. Kickoff from Canvas Stadium in Fort Collins, CO is scheduled for 9 p.m. ET on CBS Sports Network.

Colorado State (0-1, 0-1 Mountain West) has not won since posting a 37-17 home victory over UNLV on Nov. 2, 2019. Wyoming (1-1, 1-1) bounced back from a season-opening overtime loss at Nevada to rout Hawaii 31-7 last Friday. The Cowboys are 3.5-point favorites in the latest Wyoming vs. Colorado State odds from William Hill, while the over-under for total points scored is 53.5. Before making any Colorado State vs. Wyoming picks, check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $4,100 for $100 players on its top-rated college football picks against the spread. It is a sizzling 31-19 on top-rated picks through nine weeks of the 2020 college football season, returning over $600 in profit already. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Wyoming vs. Colorado State. You can visit SportsLine now to see the picks. Here are the college football odds from William Hill and trends for Colorado State vs. Wyoming:

  • Wyoming vs. Colorado State spread: Cowboys -3.5
  • Wyoming vs. Colorado State over-under: 53.5 points
  • Wyoming vs. Colorado State money line: Cowboys -160, Rams +140
  • WYO: The Cowboys are 6-1 against the spread versus teams with losing records
  • CSU: The Rams are 8-3 ATS in their last 11 Thursday games

Why Wyoming can cover

Colorado State limited Fresno State to 84 yards on the ground in its season-opening loss and will need another strong effort on Thursday. The Cowboys ran for 281 yards en route to their 31-7 victory over Hawaii last Friday, with Xazavian Valladay leading the way. The junior gained 163 yards against the Rainbows for his ninth career 100-yard performance and scored two of Wyoming's four rushing touchdowns.

Valladay also had a field day in last year's 17-7 win over the Rams, amassing 154 yards on 27 carries. The Cowboys should get Isaiah Neyor more involved in the offense versus Colorado State. The freshman wide receiver did not have a reception against Hawaii after making three catches for a team-high 102 yards in the season-opening loss at Nevada.

Why Colorado State can cover

After two seasons at Temple and seven at Boston College, coach Steve Addazio is looking to keep the Rams from enduring a third consecutive losing campaign. He may have a choice to make at quarterback on Thursday as juniors Todd Centeio and Patrick O'Brien both saw action in the season opener. Centeio threw for 141 yards and ran for a team-leading 89 while O'Brien completed 7-of-10 passes, including one for a touchdown.

O'Brien, who played at Nebraska in 2017 before joining the Rams last year, has experience against Wyoming. In last season's 17-7 road loss, he was 17-of-29 for 217 yards with one touchdown and one interception. Tight end Trey McBride figures to be the top target of either quarterback after leading Colorado State with eight catches for 130 yards and a TD in the season opener.

How to make Wyoming vs. Colorado State picks

SportsLine's model is leaning over on the total, and it says four different Wyoming players rush for at least 55 yards. It also has generated an against-the-spread pick that cashes in well over 60 percent of simulations. You can only get the pick at SportsLine.

So who wins Colorado State vs. Wyoming? And which side of the spread cashes in well over 60 percent of simulations? Visit SportsLine now to see which side of the Wyoming vs. Colorado State spread to jump on, all from the advanced model that is up over $4,100 on its top-rated college football picks over the past four-plus seasons, and find out.