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The 2022 World Series continues with Game 3 on Tuesday evening after Monday's game was cancelled due to rain. The Philadelphia Phillies host the Houston Astros at Citizens Bank Park, with the series knotted at 1-1. Lance McCullers Jr. gets the start for the Astros, while Ranger Suarez takes the hill for the Phillies. McCullers is 0-0 with a 2.45 ERA this postseason, while Suarez is 1-0 with a 1.86 ERA.

First pitch is at 8:03 p.m. ET in Philadelphia. Caesars Sportsbook lists Houston as the -125 favorite (risk $125 to win $100) on the money line, while the over/under, or total number of runs Vegas thinks will be scored, is 8 in the latest Astros vs. Phillies odds. Before making any Phillies vs. Astros picks, check out the latest MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it entered the 2022 World Series on a 20-13 roll on top-rated MLB money-line picks, returning more than $400. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen huge returns.

Now, the model has dialed in on Astros vs. Phillies and just revealed its coveted World Series 2022 picks and predictions. You can visit SportsLine now to see the model's MLB picks. Here are the MLB odds and World Series betting lines for Phillies vs. Astros:

  • Astros vs. Phillies money line: Astros -125, Phillies +105
  • Astros vs. Phillies over/under: 8 runs
  • Astros vs. Phillies run line: Astros -1.5 (+140)
  • HOU: The Astros are 16-5 with one day off between games in 2022
  • PHI: The Phillies are 11-9 with one day off between games in 2022
  • Astros vs. Phillies picks: See picks at SportsLine

Why you should back the Astros

Houston's pitching has been dominant thus far in the postseason. In fact, the Astros' pitching staff features a 2.18 ERA through nine playoff games. McCullers last faced the Phillies on Oct. 3, giving up six hits and just one run while striking out five. The 29-year-old right-hander started eight games in the regular season, recording 50 strikeouts over 47.2 innings of work.

Offensively, the Astros feature several players who can provide a spark. Yordan Alvarez posted a .306/.406/.613 slash line during the 2022 regular season, blasting 37 home runs and generating 29 doubles. In Houston's 5-2 victory over the Phillies in Game 2, Alvarez recorded a hit, two runs scored and an RBI. 

Why you should back the Phillies

The extra day certainly could play to Philadelphia's advantage. Suarez is the No. 3 starter for the Phillies and likely would've started on Monday night had he not been needed out of the bullpen in Game 1 last Friday. He only threw 11 pitches in that outing and he hasn't had a full start since Oct. 21, so he should be fresh for this one. He's been great in the 2022 MLB playoffs, giving up just two earned runs in 9.2 inning pitched.

Bryce Harper has been arguably the best hitter in the postseason, posting a .392 average with five home runs and 11 RBI. Rhys Hoskins, J.T. Realmuto and Kyle Schwarber all have at least three home runs in the playoffs as well, so Philadelphia has plenty of ways to manufacture runs against a tough Astros staff. 

How to make Phillies vs. Astros picks

SportsLine's model is leaning Over on the total, projecting 8.4 combined runs. It also says one side of the money line has all the value. You can only get the model's World Series Game 3 pick at SportsLine

So who wins Astros vs. Phillies World Series Game 3? And which side of the money line has all the value? Visit SportsLine now to see which side of the Phillies vs. Astros money line to jump on, all from the advanced model that is on a 20-13 roll on top-rated MLB money-line picks, and find out.