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The San Francisco Giants will look to continue their recent dominance over the Los Angeles Dodgers and regain sole possession of the National League West Division lead when the rivals meet for the last time during the regular season on Sunday Night Baseball. The teams have split 18 games this season, but the Giants have won nine of the last 14 meetings, including three of the last five at San Francisco. The Dodgers (86-50) have played well on the road in 2021, going 40-27. The Giants (86-50), meanwhile, have the third-best home record in MLB at 44-23. Only the Dodgers and Colorado Rockies are better.

First pitch from Oracle Park in San Francisco is set for 7:08 p.m. ET. The Giants lead the all-time series 1,268-1,247, while the Giants own a 675-575 edge in games played at home. The Dodgers are a –190 favorite (risk $190 to win $100) on the money line in the latest Dodgers vs. Giants odds from Caesars Sportsbook, while the over-under for total runs scored is 8.5. Before making any Giants vs. Dodgers picks, check out the latest MLB predictions from the SportsLine Projection Model.

This model, which simulates every game 10,000 times, is 176-142 on top-rated MLB money-line picks through 22 weeks in the 2021 season, returning almost $1,000. It also had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line MLB picks. Anyone following it has seen some huge returns.

Now, the model has locked in its Dodgers vs. Giants picks and predictions. You can visit SportsLine now to see its MLB picks. Here are the MLB odds today and betting trends for Giants vs. Dodgers:

  • Dodgers vs. Giants money line: Los Angeles -190, San Francisco +170
  • Dodgers vs. Giants run line: Los Angeles -1.5 (-120)
  • Dodgers vs. Giants over-under: 8.5 runs
  • LAD: The Dodgers are 7-1 in their last eight road games
  • SF: The Giants are 16-6 in their last 22 of a Game 3 in a series

Why you should back the Giants

Kris Bryant has been a big addition to San Francisco's lineup since being acquired at the trade deadline from the Chicago Cubs. In 27 games with the Giants, Bryant is hitting .267 with eight doubles, six homers and 14 RBIs. He has hits in eight of the last 11 games, including a 2-for-4 performance against the Dodgers on Saturday night. In 39 career games against the Dodgers, Bryant is hitting .244 with seven doubles, one triple, 10 homers and 18 RBIs.

Infielder Evan Longoria has returned from the injured list and is expected to give the Giants' offense a needed boost. On Saturday, Longoria made his first start since suffering a hand injury on Aug. 18 against the New York Mets and went 1-for-4. For the season, he is hitting .287 with 10 homers, 31 RBIs and 32 runs scored. He's had some success against the Dodgers this year. In eight games, he is batting .259 with a double, two homers and six RBIs. 

Why you should back the Dodgers

The defending World Series champions have been on fire, winning seven of their past 10 games. Right-hander Walker Buehler (13-2, 2.05 ERA) is expected to take the mound for Los Angeles. He will be making his 28th start of the year and has not lost since a 3-0 decision to Houston on Aug. 3. He has won two of his last five starts. In his last appearance on Tuesday against Atlanta, he received a no-decision, but held the Braves to two earned runs on four hits in seven innings. He walked two and struck out five. In five starts against the Giants in 2021, he is 3-0 with a 0.79 ERA.

Offensively, third baseman Justin Turner has been red hot with a five-game hitting streak. He was 2-for-4 in both Monday and Tuesday's games against Atlanta. For the season, Turner is batting .282 with 21 homers, 71 RBIs and 71 runs scored with a .466 slugging percentage and .838 OPS. He has had a lot of success against San Francisco, batting .292 against the Giants in his career. 

How to make Giants vs. Dodgers picks

SportsLine's model is leaning under on the total, as the simulations project both teams combine for 8.2 runs. The model also says one side of the money line has the value. You can only get its Sunday Night Baseball picks at SportsLine

So who wins Dodgers vs. Giants? And which side of the money line has all the value? Visit SportsLine now to see the top picks for Giants vs. Dodgers on Sunday Night Baseball, all from the advanced model that has crushed its MLB picks in 2021.