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The Baltimore Orioles aim to bounce back on Saturday afternoon. Baltimore lost a Friday night tilt to the Minnesota Twins despite a ninth inning lead on the road. That was the third straight loss for the Orioles and now they have a quick turnaround with a day game on Saturday. Minnesota is 24-17 at home and 44-36 overall this season, competing for playoff positioning at the highest level of the American League.

Caesars Sportsbook lists Minnesota as the -240 money-line favorite (risk $240 to win $100) for this 2:10 p.m. ET first pitch. The total number of runs Vegas thinks will be scored, or the over-under, is nine in the latest Twins vs. Orioles odds. Before making any Orioles vs. Twins picks, you need to see the MLB predictions and betting advice from SportsLine's advanced computer simulation model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 59-51 run on top-rated MLB money-line picks through 12 weeks. This is the same model that pegged the 2021 Atlanta Braves as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Orioles vs. Twins, and just locked in its picks and MLB predictions. You can head to SportsLine now to see its picks. Now, here are several MLB odds and betting lines for Twins vs. Orioles:

  • Twins vs. Orioles money line: Twins -240, Orioles +196
  • Twins vs. Orioles over-under: 9 runs 
  • Twins vs. Orioles run line: Twins -1.5 (-115)
  • BAL: The Orioles are 15-15 in day games 
  • MINN: The Twins are 21-17 in day games
  • Twins vs. Orioles picks: See picks here.
Featured Game | Minnesota Twins vs. Baltimore Orioles

Why you should back the Orioles

Baltimore has offensive strengths to note in this matchup. The Orioles currently rank in the top five of the American League with 138 doubles, and also has 11 triples. Team speed is a strength for Baltimore, as evidenced by a top-five mark in the league in stolen bases, and the Orioles are facing a Twins team that ranks dead-last in the American League in wins above replacement from its bullpen. 

On the pitching side, Orioles starter Jordan Lyles has limited opponents to a .621 OPS in his last two outings, and Baltimore's bullpen has a tremendous profile in 2022. The Orioles lead the AL in WAR from relievers, and Baltimore's relief corps has a 3.20 ERA. Baltimore's relievers also sport a 48.2 percent ground ball rate that ranks No. 2 in the American League, with the Orioles giving up only 3.09 walks and 0.73 home runs per nine innings with relief pitchers on the mound.

Why you should back the Twins

Minnesota's offense is highly potent, with top-tier marks in several key areas including runs, hits, home runs, doubles and slugging percentage. The Twins are in the top three of the American League in total bases, and they have the offensive edge against Baltimore. From there, Minnesota also has an elite starting pitching option in Sonny Gray. The 32-year-old right-hander is a two-time All-Star, and he is excelling with a 2.17 ERA this season. 

Gray is averaging 8.9 strikeouts and 2.0 walks per nine innings with a 0.97 WHIP in 2022. He has not allowed more than three earned runs in any start this season, and Gray owns a 1.66 ERA since May 1. Opponents have a .564 OPS against Gray this season, and Baltimore's offense is weak in the aggregate. The Orioles are soundly below the American League average in runs scored, hits, walks, strikeout avoidance, batting average, on-base percentage, slugging percentage and total bases this season.

How to make Orioles vs. Twins picks

SportsLine's model is leaning under on the total, and it says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Orioles vs. Twins? And which side has all the value? Visit SportsLine now to see which side of Orioles vs. Twins you need to jump on Saturday, all from the model that has crushed its MLB picks, and find out.