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The Boston Celtics can forge a three-way tie atop the Eastern Conference standings when they host Miami Heat in a crucial matchup on Wednesday at TD Garden in Boston. The Celtics (47-29), who had their six-game winning streak ended in an overtime loss at Toronto on Monday, enter the game in third place in the East, one game behind East-leading Miami (48-28) and a half game behind second place Milwaukee (47-28). A Boston win would create a three-way tie atop the conference with less than two weeks remaining in the regular season. 

Tip-off is 7:30 p.m. ET. Boston is listed as a five-point favorite in the latest Celtics vs. Heat odds from Caesars Sportsbook while the Over/Under for total points scored is 213.5. Before making any Heat vs. Celtics picks or NBA predictions, you need to see the NBA predictions and betting advice from SportsLine's advanced computer simulation model

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 24 of the 2021-22 NBA season on a stunning 83-51 roll on all top-rated NBA picks, returning over $2,600. Anyone following it has seen huge returns.

Now, the model has set its sights on Celtics vs. Heat, and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and betting lines for Celtics vs. Heat:

  • Celtics vs. Heat spread: Boston -5
  • Celtics vs. Heat over-under: 213.5 points
  • Celtics vs. Heat money line: Boston -210, Miami +175
  • BOS: The Celtics lead the league in defensive efficiency (105.9 points per 100 possessions)
  • MIA: Bam Adebayo leads all centers in steals per game (1.47)
Featured Game | Boston Celtics vs. Miami Heat

Why the Celtics can cover

Jayson Tatum is on a roll as the 6-foot-8 forward has been named the Eastern Conference Player of the Week in each of the last two weeks. Last week he averaged 32.0 points, 5.0 rebounds and 5.0 assists while shooting 58.2 percent from the field and 50.0 percent on 3-pointers and helped Boston to a 3-0 record.

In addition, Boston's stars are rested for this matchup. Tatum and Jaylen Brown did not play on Monday in Toronto because of minor issues, and Al Horford did not play because of personal reasons. Yet, the shorthanded Celtics nearly knocked off the Raptors in overtime. All three are expected to play on Wednesday while Robert Williams III (knee) is out.

Why the Heat can cover

Bam Adebayo is having an NBA Defensive Player of the Year-caliber season. The multi-dimensional defender leads all centers in steals per game (1.47). He also is holding guards to just 38.4 percent shooting from the field, including 34.6 percent from the 3-point line. He also anchors a defense that is giving up just 105.2 points per game, the fourth-lowest in the NBA.

In addition, Miami has the league's best sixth man in Tyler Herro. The 6-foot-5 guard is averaging an NBA-best 20.8 points off the bench this season (Jordan Clarkson is second, at 16.0). He has scored 1,063 points off the bench this season, the most for a single season in Heat history, surpassing Dwyane Wade for the all-time record.

How to make Heat vs. Celtics picks

SportsLine's model is leaning over on the total, projecting 219 combined points. The model also says one side of the spread hits in almost 60 percent of simulations. You can only see the model's Heat vs. Celtics picks at SportsLine.

So who wins Celtics vs. Heat? And which side of the spread hits in nearly 60 percent of simulations? Visit SportsLine now to see which side of the Heat vs. Celtics spread you need to jump on Wednesday, all from the model that has crushed its NBA picks, and find out.