With what most believed to be solid rosters in place, many expected the Los Angeles Lakers and New York Knicks to be serious threats in their respective conferences during the 2021-22 NBA season. However, if the 2022 NBA playoffs were to start today, both franchises would miss the postseason. But there's still over a third of the season left and both sides will be chasing a needed victory when they go head-to-head on Saturday.

The game will be played at Crypto.com Arena in Los Angeles and tipoff is scheduled for 8:30 p.m. ET. Both teams have lost four of their last five games, but Los Angeles is the 4.5-point home favorite with the over-under at 213.5 in the latest Lakers vs. Knicks odds from Caesars Sportsbook. Before finalizing any Lakers vs. Knicks picks, be sure to see the NBA predictions and betting advice from SportsLine's proven computer model

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model enters Week 16 of the 2021-22 NBA season on a stunning 62-32 roll on all top-rated NBA picks, returning over $2,500. Anyone following it has seen huge returns.

Now, the model has set its sights on Knicks vs. Lakers, and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model's picks. Here are several NBA betting lines and trends for Lakers vs. Knicks:

  • Knicks vs. Lakers spread: Lakers -4.5
  • Knicks vs. Lakers over-under: 213.5 points
  • Knicks vs. Lakers money line: Los Angeles -200, New York +170
  • LAL: They are 8-4 ATS with the rest advantage this season.
  • NYK: They are 10-5 ATS when they've had more time to rest.
Featured Game | Los Angeles Lakers vs. New York Knicks

Why the Lakers can cover

The Lakers are coming off a tough 111-110 loss to the Clippers at Crypto.com Arena on Thursday where they played as the road team. LeBron James rested during that game because of knee swelling and though he's considered doubtful for Saturday's contest, there appears to be at least a chance he could play. Carmelo Anthony (hamstring), however, has been ruled out for this one. Anthony Davis had 30 points and 17 rebounds in the loss and also had 30 points and 15 rebounds in a win over the Trail Blazers on Wednesday.

Davis will obviously have to continue carrying a heavy load, and Russell Westbrook will also have to prove that he can still be dominant with the ball in his hands. Westbrook had 17 points, six rebounds and four assists in just over 35 minutes and went 7-for-18 from the floor in Thursday's loss. He's averaging a disappointing 18.7 points, 7.8 rebounds and 7.7 assists per game this season after averaging a triple-double per game in three of his last four seasons before joining the Lakers.

Why the Knicks can cover

New York's strength is its defense, as it allows less than 105 points per game (sixth in NBA), with its opponents shooting just 44 percent (third). It has held opponents under 100 six times in the past 13 games, and the Lakers shot just 37.4 percent from the field in the November victory. Julius Randle had 20 points and 16 rebounds, with 15 of his boards coming on the defensive end. He leads the team with 18.7 points and 9.9 rebounds per game. Evan Fournier was the top scorer in the November victory with 26 points, hitting six of his nine 3-point attempts.

The Knicks hit 15 of their 34 3-point tries in that matchup, and they hit more than 45 percent of their shots from the field. They haven't been shooting well overall this season, but they can hit their outside shots, and the Lakers' perimeter defense has been struggling recently. New York is 11th in the NBA in hitting 35.7 percent from beyond the arc, and the Clippers hit more than 43 percent in Thursday's game against the Lakers. Fournier is averaging 3.6 made 3-pointers over the last 10 games, and he is hitting 40.3 percent from 3-point range for the season.

How to make Knicks vs. Lakers picks

SportsLine's model is leaning under on the total, projecting 209 combined points. The model also says one side of the spread hits well over 50 percent of the time. You can only see the model's pick at SportsLine.

So who wins Knicks vs. Lakers? And which side of the spread hits well over 50 percent of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its NBA picks, and find out.