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Saturday's NFL DFS player pool is loaded with talent, even though there is only one game on the schedule. Dallas and Detroit have two of the league's best offenses, and they also play at a fast pace, so there will be scoring opportunities galore on Saturday at 8:15 p.m. ET. Cowboys quarterback Dak Prescott has been held under 300 passing yards in four straight games, including a 134-yard outing against Buffalo two weeks ago. Should you avoid Prescott with your Saturday NFL DFS lineups?

Lions quarterback Jared Goff has not cracked the 300-yard mark in his last four games either, so that will be a target for both signal callers in Saturday's showdown. Which quarterback should you include in your Week 17 NFL DFS strategy? Before making any NFL DFS picks for Lions vs. Cowboys on sites like DraftKings and FanDuel, be sure to check out the NFL DFS lineup advice, strategy and player stacks from SportsLine NFL daily Fantasy expert Jimmie Kaylor

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who cashed big all season in 2022, has covered the NFL and college football for over a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.  

Kaylor hit on epic NFL DFS picks all season in 2022. He was all over Travis Kelce's four-touchdown performance against the Raiders on Monday Night Football, Kirk Cousins' 460-yard, four-TD performance on Thanksgiving Day, and T.J. Hockenson's 13 catches for 109 yards and two touchdowns in Week 15.

This year, Kaylor has been all over players like Justin Jefferson (11-159), D'Andre Swift (175-1), DeVonta Smith (4-132-1), T.J. Hockenson (7-66-2), D.J. Moore (8-230-3), David Montgomery (121-3), Ja'Marr Chase (12-141, 11-149-1), Alvin Kamara (12-91, 76), Jordan Addison (7-123-2), Jahmyr Gibbs (152-1, 5-37), Javonte Williams (79, 3-31-1), Dak Prescott (331-4), CeeDee Lamb (12-116-1), DK Metcalf (6-143-3), Aidan O'Connell (248-4), and Puka Nacua (9-164-1) in single-game slates. Anyone who followed his picks cashed in big.

Now, Kaylor has turned his attention to Cowboys vs. Lions on Saturday night and just locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.

Top NFL DFS picks for Lions vs. Cowboys on Saturday

One of Kaylor's top NFL DFS picks for Saturday night is Cowboys wide receiver CeeDee Lamb. He has bolstered NFL DFS lineups throughout the season, going over 100 receiving yards on seven occasions. He had one of those outings last week, racking up six receptions for 118 yards and one touchdown against Miami.

Lamb has caught at least six passes in nine of his last 10 games, and he has scored eight touchdowns during that stretch. He has added some versatility on the ground as well, turning 12 carries into 101 yards and two touchdowns. The 24-year-old is facing a Lions defense that is No. 23 in the NFL against the pass, allowing 234.9 passing yards per game. 

Part of Kaylor's optimal NFL DFS strategy also includes rostering Detroit wide receiver Amon-Ra St. Brown. The third year pro is also having a career year in 2023, and enters this matchup with 106 receptions for 1,281 yards and eight touchdowns. Dallas has one of the league's best defenses, but Kaylor still believe St. Brown will be productive on Saturday night. 

"Amon-Ra St. Brown and Jared Goff have an obvious rapport, and the former USC wide receiver's route running ability makes him a nearly matchup proof fantasy option. St. Brown and the Lions will face a stiff test from the Cowboys' defense, but I still expect them to score and continue racking up explosive plays. I am projecting another 10+ target game for St. Brown on Saturday night," Kaylor said. You can see the rest of Kaylor's NFL DFS picks here.

How to build NFL DFS lineups for Cowboys vs. Lions on Saturday

Kaylor is also targeting another undervalued player who could explode for huge numbers on Saturday night. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of Kaylor's TNF DFS picks, at SportsLine

So who is Jimmie Kaylor including in his optimal NFL DFS lineups for Lions vs. Cowboys on Saturday, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a DFS expert who already won a single-game millionaire maker tournament, and find out.