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The Los Angeles Rams hope their new home field remains an advantage when they host the first-place Seattle Seahawks in an NFC West showdown on Sunday. The Rams (5-3) have won all three of their games in the state-of-the-art SoFi Stadium. They won the last meeting between the teams, easing to a 28-12 victory when Seattle (6-2) visited the Coliseum late last season. The Rams' defense has been stellar and quarterback Jared Goff has been playing well, while Seahawks QB Russell Wilson leads the league's top passing offense, but both teams have had issues with turnovers.

Kickoff is set for 4:25 p.m. ET at SoFi Stadium. Los Angeles is a 2.5-point favorite in the latest Seahawks vs. Rams odds at William Hill Sportsbook, while the Over-Under for total points scored is 54.5. Before making any Rams vs. Seahawks picks, be sure to check out the latest NFL predictions from the SportsLine Projection Model

The model, which simulates every NFL game 10,000 times, is up over $7,600 for $100 players on top-rated NFL picks since its inception five-plus years ago. It's off to a strong 16-9 roll on top-rated NFL picks this season. The model also enters Week 10 on an incredible 112-74 run on top-rated NFL picks that dates back to the 2017 season. 

The model ranked in the Top 10 on NFLPickWatch three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up. 

Now, the model has broken down Rams vs. Seahawks. You can head to SportsLine to see the picks. Here are the NFL odds and trends for Seahawks vs. Rams:

  • Seahawks vs. Rams spread: Los Angeles -2.5
  • Seahawks vs. Rams over-under: 54.5
  • Seahawks vs. Rams money line: Seattle +125, Los Angeles -140
  • SEA: WR DK Metcalf has 19 catches for 269 yards and three TDs in the last two games
  • LAR: RBs Darrell Henderson and Malcolm Brown have a combined 772 yards and six rushing TDs

Why the Rams can cover

Los Angeles is 16-5-1 against the spread in its last 22 games versus NFC teams, and the defense could rattle Wilson, who has tossed eight interceptions, fourth-most in the league. He also has been sacked 24 times and now faces a defense that has 24 takedowns. L.A.'s defense is second in the league against the pass (197.1 per game).

The Rams, who are 5-1-1 against the spread in their last seven games as home favorites, also run a balanced offense led by Goff. The veteran threw for a season-high 355 yards in a 28-17 loss to Miami last week, with Cooper Kupp catching 11 balls for 110 yards.

Goff counts heavily on Kupp (48 receptions) and wide receiver Robert Woods (37), while tight ends Tyler Higbee and Gerald Everett have 20 catches apiece. The Rams also rush for 137.8 yards per game (seventh in the NFL).

Why the Seahawks can cover

Seattle is 9-2 against the spread in its last 11 games as a road underdog, and quarterback Russell Wilson and receiver DK Metcalf have been carrying the team. Wilson is fourth in the NFL with 2,541 yards and has a league-high 28 TD passes. Metcalf has 788 yards through eight games (second in NFL) and scored eight times (second). Wilson also counts on Tyler Lockett (615 yards and seven scores) and David Moore (15.8 yards per catch).

Seattle's defense has 14 takeaways, with nine interceptions, and three defensive backs have two picks apiece. K.J. Wright, who is fighting an ankle injury, has a pick and two fumble recoveries, while fellow linebacker Bobby Wagner provides tackles (80) and leadership. Safety Jamal Adams has 3.5 of the team's 19 sacks.

How to make Rams vs. Seahawks picks

The model is leaning under the total, calling for 52 points. It also has generated a strong against-the-spread pick that cashes in well over 50 percent of simulations. You can only see it here.

So who wins Rams vs. Seahawks? And which side of the spread can you bank on in well over 50 percent of simulations? Visit SportsLine right now to find out which side of the Seahawks vs. Rams spread you should be all over Sunday, all from the model on a 112-74 roll on its top-rated NFL picks.