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The Minnesota Golden Gophers and the No. 19 Michigan State Spartans are set to square off in a Big Ten matchup at 9 p.m. ET on Wednesday at Williams Arena. The Golden Gophers are 7-0 overall and 3-0 at home, while the Spartans are 7-2 overall and 1-0 on the road. The Spartans have won eight of the last 10 head-to-head matchups and covered in seven of those contests.

However, it was Minnesota who got the 81-56 win as three-point underdogs when the two teams last met in December 2020. This time around, the Spartans are favored by seven points in the latest Minnesota vs. Michigan State odds from Caesars Sportsbook and the over-under is set at 135. Before entering any Michigan State vs. Minnesota picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Minnesota vs. Michigan State. You can head to SportsLine to see its picks. Here are several college basketball odds for Michigan State vs. Minnesota:

  • Minnesota vs. Michigan State spread: Minnesota +7
  • Minnesota vs. Michigan State over-under: 135 points
Featured Game | Minnesota Golden Gophers vs. Michigan State Spartans

What you need to know about Minnesota

Even if it wasn't a dominant performance, Minnesota beat the Mississippi State Bulldogs 81-76 on Sunday in Starkville. Minnesota's guard Payton Willis had a strong game with 24 points and seven assists. That high-scoring win came on the heels of a grind-it-out 54-53 win over Pitt on the road the week prior.

Now Minnesota is riding high coming home and heading into Big Ten play and Willis has been a huge factor in his return to Minnesota. Willis began his career at Vanderbilt, transferred to Minnesota, transferred as a graduate student to College of Charleston and used his additional eligibility to transfer back to Minnesota. He's averaging 17.4 points, 5.1 rebounds and 3.9 assists per game this season.

What you need to know about Michigan State

Meanwhile, while not quite a landslide, the contest between the Spartans and the Toledo Rockets this past Saturday was still a pretty decisive one as Michigan State wrapped it up with an 81-68 win at home. Five players on Michigan State scored in double digits: guard Max Christie (14), forward Gabe Brown (12), guard Tyson Walker (11), forward Marcus Bingham Jr. (10), and guard A.J. Hoggard (10).

Michigan State's only losses this season came to Kansas and Baylor on neutral floors but it has wins over Louisville, Loyola Chicago, Connecticut and Butler. Brown is averaging 12.9 points per game this season to lead the team in scoring and the fourth-year forward is shooting 35.4 percent from the 3-point line. He and the rest of the Spartans will have to work hard from quality looks from outside against a Minnesota defense that ranks third in 3-point field goal percentage allowed (23.1 percent).

How to make Minnesota vs. Michigan State picks

The model has simulated Minnesota vs. Michigan State 10,000 times and the results are in. We can tell you that the model is leaning over and it's also generated a point-spread pick that is hitting in well over 80 percent of simulations. You can only see the pick at SportsLine.

So who wins Michigan State vs. Minnesota? And which side of the spread hits well over 80 percent of the time? Visit SportsLine now to find out, all from the red-hot model that has crushed its college basketball picks.