The No. 16 Ohio State Buckeyes and the Michigan Wolverines will face off in a Big Ten clash at 6 p.m. ET on Saturday at the Crisler Center. Michigan is 13-9 overall and 8-2 at home, while the Buckeyes are 14-6 overall and 3-5 on the road. The Wolverines are coming off their biggest win of the season, as they took down No. 3 Purdue in blowout fashion on Thursday. 

The Wolverines are favored by 2.5 points in the latest Michigan vs. Ohio State odds from Caesars Sportsbook, while the over-under is set at 141. Before entering any Ohio State vs. Michigan picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,300 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Michigan vs. Ohio State. You can head to SportsLine to see its picks. Here are several college basketball odds for Ohio State vs. Michigan:

  • Michigan vs. Ohio State spread: Michigan -2.5
  • Michigan vs. Ohio State over-under: 141 points
Featured Game | Michigan Wolverines vs. Ohio State Buckeyes

What you need to know about Michigan

Michigan was in desperate need of a resume-building win, and it came up with one on Thursday night. The Wolverines crushed No. 3 Purdue in an 82-58 blowout, picking up their first win over a ranked opponent this season. It was also the highest-ranked win for head coach Juwan Howard, whose previous best came in a win at No. 4 Ohio State last season. 

Big man Hunter Dickinson led Michigan with 22 points, knocking down a career-high four 3-pointers. Guard Eli Brooks added 18 points, including a 4 of 4 mark from beyond the arc. The Wolverines are on a five-game home winning streak, but they are still on the NCAA Tournament bubble. 

What you need to know about Ohio State

Ohio State was unable to build on its 82-67 win over Maryland on Sunday, losing to Rutgers on Wednesday night. The Buckeyes have now split their last four games, dropping to fifth place in the Big Ten standings. They are 3-4 in their seven conference road games this season. 

The Buckeyes are scheduled to play six of their final eight games at home. Junior forward E.J. Liddell leads Ohio State with 19.7 points and 7.6 rebounds per game, while freshman guard Malaki Branham is adding 10.9 points. The Buckeyes have covered the spread in six of the last nine meetings between these teams. 

How to make Ohio State vs. Michigan picks

The model is leaning over on the total, and it's also generated a point-spread pick that is hitting in 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Ohio State vs. Michigan? And which side covers 60 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its college basketball picks.