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The No. 4 Connecticut Huskies (11-2) play the DePaul Blue Demons (3-9) in a Big East showdown on Tuesday evening. The Huskies have dominated the series against DePaul, winning 15 straight. UConn blew out the Blue Demons 88-59 in March of 2023. UConn center Donovan Clingan (foot) is out for this game. 

Tipoff from Gampel Pavilion in Connecticut is set for 6:30 p.m. ET. The Huskies are 23.5-point favorites in the latest DePaul vs. UConn odds via SportsLine consensus, while the over/under for total points scored is 137.5. Before making any UConn vs. DePaul picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division I college basketball game 10,000 times. It enters Week 9 of the 2023-24 season on a 101-66 roll on all top-rated college basketball picks dating back to last season, returning more than $2,000 for $100 players. It is also off to a fast 11-4 start on top-rated spread picks this season. Anyone following has seen huge returns.

The model has set its sights on UConn vs. DePaul. You can head to SportsLine to see its picks. Here are several college basketball betting lines and trends for DePaul vs. UConn:

  • UConn vs. DePaul spread: Huskies -23.5
  • UConn vs. DePaul over/under: 137.5 points
  • UConn vs. DePaul money line: Huskies -8000, Blue Demons +1760
  • DEP: 4-8 ATS this season 
  • CONN: Has hit the team total Over in 9 of last 12 games
  • UConn vs. DePaul picks: See picks at SportsLine

Why UConn can cover

Sophomore forward Alex Karaban is a versatile offensive player who has a good feel for the game and a soft touch on his jumpers. The Massachusetts native averages 14.2 points and 5.9 rebounds per game. Additionally, he's fourth on the team in field-goal percentage (51%). In the Dec. 9 victory over Arkansas-Pine Bluff, Karaban finished with a season-high 26 points, seven boards and went 6-of-9 from downtown.

UConn is 7-5 ATS as a favorite this year and it has covered in three of its last five overall. The Huskies have also been a solid team to bet on when they have extended rest as they are 6-3 ATS with four or more days between games. See who to back at SportsLine

Why DePaul can cover

Senior guard Chico Carter Jr. can score from all three levels on the floor. Carter Jr. gets into the lane with ease but has the vision to get his teammates involved. The South Carolina native logs 13.5 points, 3.4 rebounds and 4.3 assists per game. On Dec. 9 against Louisville, Carter Jr. tallied 14 points, three boards and eight assists.

Senior forward Jeremiah Oden provides the Blue Demons with an athletic threat in the frontcourt. The Illinois native averages 11.8 points and 4.1 boards per game. He's scored 20-plus points in two of his last six games. In the Dec. 1 win over Iowa State, Oden racked up a season-high 25 points and four rebounds. See who to back at SportsLine.

How to make DePaul vs. UConn picks

The model has simulated this matchup 10,000 times and the results are in. The model is leaning Over the total, and it also says one side of the spread hits in over 50% of simulations. You can only see the picks at SportsLine.

So who wins UConn vs. DePaul, and which side of the spread hits over 50% of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that is on a 101-66 roll on its top-ranked college basketball picks, and find out.