Jacksonville quarterback Trevor Lawrence has gone over 320 passing yards in two of his last three games, finishing second in the league in passing yards (368) last week. He has thrown 10 touchdowns and zero interceptions in his last five games, making him one of the top Fantasy football picks during that stretch. Lawrence will now face a Dallas defense that has not given up more than 23 points in any of its last four games. Should you include him in your Week 15 Fantasy football lineups? Dallas quarterback Dak Prescott cooled off last week, throwing two interceptions and one touchdown in a narrow win over Houston. Prescott is a popular option in the Week 15 Fantasy football rankings, but how should you approach him with your Week 15 Fantasy football strategy? Before you lock in your lineups, be sure to check out the Week 15 Fantasy football rankings from the advanced computer model at SportsLine.

When it comes to ranking players, SportsLine's model beat human experts in Fantasy football for the past several seasons especially when there were big differences in ranking. Over the course of a season, that could literally be the difference between winning your league or going home empty handed.

Last week, the model was extremely high on Lions quarterback Jared Goff, saying he'd finish as a top-10 player at his position. The result: Goff completed 27 of 39 passes for 330 yards and three touchdowns in Detroit's 34-23 win over the Vikings. Anybody who had him in their lineup was well on their way to a huge week.

Now, the model, which simulates every NFL game 10,000 times, has revealed its Fantasy football rankings for Week 15 of the 2022 NFL season. Head to SportsLine now to see them.

Top Week 15 Fantasy football picks  

One player the model is high on this week: Broncos running back Latavius Murray. He rushed for 92 yards against Carolina at the end of November, averaging 7.1 yards per carry. Murray had a solid average against Kansas City last week as well, picking up 4.0 yards per attempt. He has been getting plenty of opportunities of late, recording at least 13 carries in four of his last six games.

Denver quarterback Russell Wilson is out with a concussion and won't play on Sunday, which could give Murray even more chances. He has been involved in the passing game as well, catching at least three passes in four of his last five games. Murray will face an Arizona defense that is No. 29 in yards per carry and No. 24 in Fantasy points per game allowed to running backs since Week 10. See who else to target here.

And a massive shocker: Buccaneers wide receiver Mike Evans, who's accumulated over 1,000 receiving yards in each of the past eight seasons, stumbles big-time and doesn't even crack the top 25 at his position. 

Evans has been a reliable Fantasy stalwart in recent years, but he's struggled mightily over the past few weeks. In fact, Evans has gone five consecutive games without reaching 60 yards and nine straight without scoring a touchdown. In addition, Evans and the Bucs will now square off against the Bengals, a defense that hasn't allowed a wide receiver to find the end zone since Nov. 20. With such a tough matchup on Sunday, Evans is a player to consider putting on the bench in Week 15. See who else to fade here

How to set Week 15 Fantasy football rankings

The model is also calling for a surprising quarterback you aren't even thinking about to finish in the top 10 of its Week 15 Fantasy football rankings. This pick could be the difference between winning big and going home with nothing. You can only see who it is here.

So who should you start and sit this week? And which surprising quarterback could lead you to victory? Visit SportsLine now to get Week 15 Fantasy football rankings for every position, plus see which QB is going to come out of nowhere to crack the top 10, all from the model that has outperformed experts big-time.