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Stan Szeto / USA TODAY Sports

The Houston Astros have reached the American League Championship Series each of the last three seasons, winning it twice. Despite having finished the shortened 2020 MLB season with just a 29-31 record, they took the first step toward a fourth consecutive berth by making easy work of the Central Division-champion Minnesota Twins in the Wild Card Series. The next stage of the process for the Astros begins Monday, when they face the AL West-rival Oakland Athletics in Game 1 of the AL Division Series.

First pitch at Dodger Stadium in Los Angeles is set for 4:07 p.m. ET. Oakland is the -135 favorite on the money line in the latest Astros vs. Athletics odds from William Hill, while the over-under for total runs scored is eight. Before making any Athletics vs. Astros picks, check out the latest MLB predictions from the SportsLine Projection Model

This model, which simulates every pitch 10,000 times, returned more than $1,400 on its top-rated money-line and run-line picks, and anyone who followed it saw huge rewards. It also got off to a hot start in the first week of the 2020 MLB Playoffs, hitting all three top-rated money-line MLB picks -- including the Cardinals (+150) in Game 1 against the Padres -- and returning almost $300 on the week. 

Now, the model has dialed in on Astros vs. A's. You can visit SportsLine now to see the picks. Here are the MLB odds from William Hill and trends for A's vs. Astros:

  • Athletics vs. Astros money line: Oakland -135, Houston +125
  • Athletics vs. Astros run line: Oakland -1.5
  • Athletics vs. Astros over-under: 8 runs
  • OAK: 1B Matt Olson has struck out in six of his nine at-bats this postseason
  • HOU: 1B Yuri Gurriel is 7-for-19 lifetime against Athletics RHP Chris Bassitt

Why you should back the Athletics

Oakland ended Houston's three-year reign atop the AL West this year, winning its first division title since 2013. The Athletics finished seven games ahead of the Astros in the standings as they won seven of the 10 meetings between the rivals. Oakland held Houston to fewer than three runs in each of those victories.

Bassitt, who recorded a career-high 10 wins in 2019, continued his success this year as he went 5-2 with a 2.29 ERA over 11 starts. The 31-year-old right-hander was superb in September, allowing a total of one run over 26 ⅔ innings in four outings. Bassitt also was stellar against the White Sox in Game 2 of the Wild Card Series as he yielded just one run over seven innings en route to help keep alive the Athletics' season.

Why you should back the Astros

Despite losing the season series this year, Houston is no stranger to success when it comes to facing the Athletics. Over the previous three campaigns, the Astros posted a 35-22 record in the series. Houston has not been fazed on the road in the postseason lately, winning five straight road playoff games and seven of its last eight.

Like Bassitt, Lance McCullers Jr. finished the regular season on a strong note. The 27-year-old righty went 0-1 over his final three starts but did not allow an earned run over 17 ⅔ innings in those outings. McCullers will be hoping for some support from his offense on Monday as the Astros failed to score a run while he was on the mound in his last three turns.

How to make Astros vs. Athletics picks

SportsLine's model is leaning under on the total, as the simulation suggests each team's bullpen well allow fewer than two runs over more than three innings, and it also says one side of the money line has the value. Head to SportsLine now to see the pick

So who wins Athletics vs. Astros? And which side of the money line has all the value? Visit SportsLine now to see which side to jump on, all from the advanced model that returned over $1,400 on MLB picks last year and got off to a hot start in the 2020 MLB Playoffs.