MLB: Los Angeles Dodgers at Atlanta Braves

The Houston Astros can extend their winning streak to nine when they host the Kansas City Royals on Wednesday in the third game of a four-game series at Minute Maid Park. The Astros (53-27) lead the AL West and have won eight straight games for the second time this season, as earlier this year they won 11 in a row. The Royals (29-50) sit at the bottom of the AL Central and are 3-7 over their last 10 contests. Houston is a -292 favorite in the latest Astros vs. Royals odds from Caesars Sportsbook while Kansas City is a +235 underdog.

First pitch is set for 8:10 p.m. ET from Houston. The game is one of 14 on the MLB schedule for Wednesday. Elsewhere in the majors, Brayan Bello, the top pitching prospect in the Red Sox system, is set to make his major league debut as he faces Tampa Bay, and reigning AL MVP Shohei Ohtani looks to extend his scoreless streak of 21.2 innings when he takes the mound against the Marlins. Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is 271-232 on top-rated MLB money-line picks since the start of the 2021 season, returning well over $500 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns. 

Now, the model has locked in four confident MLB best bets for Wednesday. The parlay doesn't start until 6:40 p.m. ET, giving you plenty of time to make your MLB picks. If you successfully parlay the picks, you'd be looking at a payout of well over 11-1. You can see the model's MLB picks for Wednesday only at SportsLine. 

Top MLB picks today

The model, which ran 10,000 simulations on each of the 14 games on Wednesday, is picking Tampa Bay (+105) to defeat Boston. Yandy Diaz has had a solid season for the Rays as the 30-year-old third baseman leads the team in batting average (.290) and on-base percentage (.405). In Tuesday's 8-4 win over the Red Sox, he went 3-for-4 with two doubles, one RBI and one run scored.

In addition Harold Ramirez has been hot at the plate for Tampa Bay. Over the last six games, the 27-year-old DH is hitting .370 and slugging .593 with an OPS of .985. He has hit safely in five of the last six games.

Featured Game | Boston Red Sox vs. Tampa Bay Rays

How to make Wednesday MLB parlays

The model also locked in three other best bets for Wednesday, including a play on a big National League underdog. You can see the model's MLB Wednesday best bets and parlay only at SportsLine.

What MLB picks should you target for a payout of well over 11-1? And what underdog does the model like on Wednesday? Visit SportsLine now to see the MLB best bets from an advanced model that is 271-232 on top-rated MLB money-line picks since the start of the 2021 season.