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The New York Yankees look to continue their torrid pace when they visit the AL East rival Baltimore Orioles on Tuesday for the second contest of their four-game series. New York, which owns the best record in the major leagues, is the only team yet to reach double digits in losses (26-9) and has won 21 of 25 games since losing two of three at Baltimore from April 15-17. The Yankees improved to 4-1 on their eight-game road trip with a 6-2 triumph in Monday's series opener. New York is a -240 money-line favorite in the latest Yankees vs. Orioles odds from Caesars Sportsbook, while Baltimore is a +200 underdog.

First pitch at Camden Yards is set for 7:05 p.m. ET. The game is one of 11 on the MLB schedule for Tuesday evening. Other matchups include the Atlanta Braves visiting the Milwaukee Brewers and the Chicago Cubs hosting the Pittsburgh Pirates in the middle contests of their three-game sets. Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times and is off to a sizzling start to the 2022 season. It's on a 33-25 roll on top-rated MLB money-line picks through six weeks, returning over $300 for $100 players. Anyone following it has seen some huge returns.

Now, the model has locked in four confident MLB best bets for Tuesday. All the games occur at 7:05 p.m. ET or later, so there's still plenty of time to make these MLB picks. If you successfully parlay the picks, you'd be looking at a payout of well over 13-1. You can only see the model's MLB picks at SportsLine.

Top MLB picks today

The model, which simulated every game on Tuesday's schedule 10,000 times, is taking Over 7.5 runs (-110) in the Pirates vs. Cubs game at 7:40 p.m. ET (see tickets at StubHub). This number has been exceeded after two innings in two of the last three meetings between the NL Central rivals. After scoring once in the opening frame on April 23, Chicago crossed the plate eight times in the second en route to a 21-0 triumph.

In Monday's series opener, the Cubs wasted little time repeating the feat as they recorded an eight-run first inning and coasted to their third straight win, a 9-0 victory. Chicago owned an 8-0 lead just 10 batters into the frame as Willson Contreras belted a grand slam in his second at-bat after leading off with a double. The contest was the seventh this season in which Pittsburgh allowed at least eight runs and marked the third time the Cubs have scored more than seven. Three of the first seven meetings between these teams have gone Over 7.5 runs, while Pittsburgh has seen 20 of its 35 overall games eclipse that mark and Chicago has had 18 of its 34 contests exceed the number.

Featured Game | Chicago Cubs vs. Pittsburgh Pirates

How to make MLB picks and parlays for Tuesday

The model also locked in three other best bets for Tuesday, including a must-see play an an underdog that wins outright well over 50 percent of the time. You can see the model's MLB best bets and parlay only at SportsLine.

What MLB picks should you target for a payout of well over 13-1? And what underdog does the model like on Tuesday? Visit SportsLine now to see the MLB best bets from an advanced model that is on a 33-25 roll on top-rated MLB money-line picks through six weeks.