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An interleague affair has the Pittsburgh Pirates (22-20) going on the road to play the Detroit Tigers (19-21) on Wednesday afternoon. Pittsburgh has been in a massive slump, dropping five of its last six games overall. Meanwhile, Detroit has won two straight matchups. On Tuesday, the Tigers beat the Pirates 4-0. Rich Hill (3-3, 4.35 ERA) is on the hill for the Pirates, while Eduardo Rodriguez (4-2, 1.57 ERA) starts for Detroit. 

First pitch is set for 1:10 p.m. ET. The Tigers are listed at -170 in the money line (risk $170 to win $100) in the latest Pirates vs. Tigers odds from Caesars Sportsbook. The over/under for total runs scored is 7.5. Before making any Tigers vs. Pirates picks, be sure to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons, It has opened the 2023 MLB season on a 20-15 roll on all-top rated MLB picks. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Pirates vs. Tigers and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB betting lines and trends for Tigers vs. Pirates:

  • Pirates vs. Tigers money line: Detroit -170, Pittsburgh +143
  • Pirates vs. Tigers run line: Pittsburgh +1.5 (-155)
  • Pirates vs. Tigers over/under: 7.5 runs
  • PIT: The Under is 4-0-1 in Pirates' last five overall
  • DET: The Tigers are 7-0 in their last seven interleague home games
  • Pirates vs. Tigers picks: See picks at SportsLine

Why you should back the Pirates

Left fielder Bryan Reynolds is a switch-hitter with good bat control and speed. Reynolds makes consistent contact and has been a run-producer for the Pirates. The 28-year-old is leading the team in batting average (.286), RBI (23), and hits (44). He's tallied a hit in five of his last six games. On May 14 against the Baltimore Orioles, he went 1-of-4 with a single and one run scored.

Designated hitter Andrew McCutchen has been an instinctive and alert player. McCutchen owns good pop in his swing with solid patience at the dish. The five-time All-Star is first on the team in home runs (7) with 18 RBI and a batting average of .246. On May 10 against the Colorado Rockies, he went 3-of-3 with a two-run homer. See which team to back here.

Why you should back the Tigers

Center fielder Riley Greene is an athletic and agile playmaker. Green has strong hands and is a pure hitter. The 22-year-old does an effective job spraying the ball all across the yard. He has a batting average of .291 along with three home runs and 15 RBI. In Sunday's win over the Seattle Mariners, he went 3-of-5 with three singles.

Shortstop Javier Baez offers tremendous bat speed and has the ability to generate plenty of pop in his swing. Defensively, Baez has a strong throwing arm with sound instincts. The 30-year-old is batting .254 with three home runs and 19 RBI. He rolls into the game on a five-game hitting streak. In his last outing, he went 1-of-4 with an RBI single. See which team to back here.

How to make Tigers vs. Pirates picks

SportsLine's model is leaning Over on the total, projecting 8.4 combined runs. It also says one side of the money line has all of the value. You can only get the model's MLB picks at SportsLine.

So who wins Pirates vs. Tigers, and which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has gone 20-15 on its top-rated MLB picks, and find out.