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Gregg Popovich and the San Antonio Spurs welcome Tom Thibodeau and the New York Knicks to town for a Tuesday night NBA matchup. The Spurs are on the second night of a back-to-back after falling to the Phoenix Suns by a 108-104 margin on Monday. San Antonio is 8-14 overall and 4-6 at home this season. New York enters on a three-game losing skid that places the Knicks under the .500 mark at 11-12 this season.

Caesars Sportsbook lists New York as a 2.5-point road favorite for this 8:30 p.m. ET tipoff. The total number of points Vegas thinks will be scored, or the over-under, is 212 in the latest Knicks vs. Spurs odds. Before making any Spurs vs. Knicks picks, be sure to see the NBA predictions and betting advice from SportsLine's proven model

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model enters Week 8 of the 2021-22 NBA season up almost $2,000 on all top-rated NBA picks this season. It's also on a stunning 121-78 roll on top-rated NBA picks against the spread that dates back to last season. Anyone following it has seen huge returns.

Now, the model has set its sights on Knicks vs. Spurs and just locked in its NBA picks and predictions. You can head to SportsLine to see the model's picks. Now, here are several NBA odds and betting trends for Spurs vs. Knicks.

  • Knicks vs. Spurs spread: Knicks -2.5
  • Knicks vs. Spurs over-under: 211 points
  • Knicks vs. Spurs money line: Knicks -150, Spurs +130
  • NYK: The Knicks are 10-13 against the spread this season
  • SAS: The Spurs are 13-9 against the spread in 2021-22
Featured Game | San Antonio Spurs vs. New York Knicks

Why the Knicks can cover

New York is led by Julius Randle, with the All-Star forward putting up 21.1 points, 10.0 rebounds and 5.3 assists per game this season. New York is in the top 10 in the NBA in 3-point accuracy (36.1 percent) and offensive rebound rate (28.1 percent), with the Knicks putting up 14.3 second-chance points per game. 

On defense, New York contests shots at an elite level, holding opponents to 43.7 percent shooting and only 50.1 percent on 2-point attempts. The Knicks are No. 3 in the NBA in points allowed in the paint (41.5 per game), with top-10 marks in second-chance points allowed (12.1 per game) and blocked shots (5.7 per game). San Antonio also struggles mightily with the free-throw line, ranking No. 29 in the league in free-throw attempts and last in the league in free-throw accuracy at only 69.8 percent.

Why the Spurs can cover

San Antonio is keyed on both ends by Dejounte Murray. The 25-year-old guard is enjoying the best season of his career, and he is known for his disruption at the point of attack defensively, using length and athleticism to deter opponents. Murray is also averaging 19.0 points, 8.5 rebounds and 8.5 assists per game for the Spurs, acting as the fulcrum of San Antonio's offensive attack. As a team, the Spurs are shooting 46.6 percent from the floor, a top-five mark in the NBA this season, and San Antonio's trademark ball movement leads to the league's No. 2 mark in assists with 27.6 per game. 

The Spurs effectively attack the rim, averaging well over 50 points in the paint per game, and San Antonio is committing only 13.1 turnovers per contest this season. With that offensive potency combined with a top-10 defense that is giving up fewer than 1.07 points per possession this season, the Spurs are more than capable of upending the Knicks in San Antonio.

How to make Spurs vs. Knicks picks

SportsLine's model is leaning under on the total as Randle and Murray both are projected to fall short of their season scoring average. The model also says one side of the spread hits in almost 60 percent of simulations. You can only see the model's pick at SportsLine.

So who wins Knicks vs. Spurs? And which side of the spread hits in almost 60 percent of simulations? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its NBA picks, and find out.