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The Green Bay Packers have ruled the NFC North, winning the division crown six of the last nine seasons. They enter Week 9 of the 2020 NFL schedule atop the NFC North standings, one-half game ahead of Chicago with a game in hand. The Packers will attempt to maintain that lead when they visit the injury-riddled San Francisco 49ers on Thursday Night Football. Kickoff from Levi's Stadium in Santa Clara, Calif. is scheduled for 8:20 p.m. ET.

Green Bay (5-2) dropped a 28-22 decision to Minnesota at home on Sunday but breathed a sigh of relief when Chicago fell to New Orleans in overtime later in the day. San Francisco (4-4) was defeated 37-27 in Seattle but lost more than the game, as quarterback Jimmy Garoppolo (ankle) and tight end George Kittle (foot) went down. Green Bay is a 6.5-point favorite in the latest 49ers vs. Packers odds from William Hill, while the over-under is 48.5. Before locking in any Packers vs. 49ers picks, make sure you see the latest Thursday Night Football predictions from SportsLine's proven projection model

The model, which simulates every NFL game 10,000 times, is up over $7,600 for $100 players on top-rated NFL picks since its inception five-plus years ago. It's off to a strong 15-8 roll on top-rated NFL picks this season. The model enters Week 9 on an incredible 111-73 run on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Niners vs. Packers. You can visit SportsLine now to see the picks. Here are the NFL odds from William Hill and trends for Packers vs. Niners:

  • Packers vs. 49ers spread: Green Bay -6.5
  • Packers vs. 49ers over-under: 48.5 points
  • Packers vs. 49ers money line: Green Bay -300, San Francisco +250
  • GB: Packers are 6-0 against the spread in their last six games following a loss
  • SF: 49ers are 7-2 against the spread in their last nine games as underdogs

Why the Packers can cover

Green Bay ranks ninth in the NFL in rushing offense (128.9 yards), which helps make Aaron Rodgers' job a bit easier. The two-time league MVP is tied for third with 20 touchdown passes and has been sacked only nine times. Rodgers has seven TD tosses in his last two contests and has been intercepted just two times, both by Tampa Bay in Week 6, this year.

Green Bay is 5-2 against the spread this season, compared to the Niners' mark of 4-4, and owns a plus-4.6 point differential. Green Bay has covered three of four road games this season.

Why the 49ers can cover

Despite being without its top two returning running backs for long portions of the season, San Francisco is tied for 10th in the NFL in rushing offense (127 yards) and ranks first with 14 touchdowns on the ground.

Rookie JaMycal Hasty led the 49ers with just 29 rushing yards against the Seahawks and ran for the first touchdown of his NFL career. Hasty is poised to carried the rushing load for the 49ers, whose point differential of plus-4.4 this season nearly matches the Packers' 4.6.

How to make 49ers vs. Packers picks

SportsLine's model is leaning under on the total. In fact, it says neither starting quarterback throws for more than 255 yards. It also says one side of the spread hits almost 60 percent of the time. You can only get the pick at SportsLine

So who wins Packers vs. 49ers on Thursday Night Football? And which side of the spread hits nearly 60 percent the time? Visit SportsLine now to see which side of the 49ers vs. Packers spread to jump on, all from the advanced model that is up more than $7,600 on its top-rated NFL picks, and find out.