Get ready for an NFC West battle Sunday as the Los Angeles Rams and San Francisco 49ers face off at 4:05 p.m. ET at Los Angeles Memorial Coliseum. The Rams are 3-2 overall and 1-1 at home this season, while San Francisco is 4-0 overall and 2-0 on the road. San Francisco and Los Angeles have both performed well against the spread, with San Francisco 3-1 and the Rams 4-1. The total has gone under in four of San Francisco's last six games, while the Rams are 8-2 against the spread in their last 10 games. Los Angeles is favored by three-points in the latest Rams vs. 49ers odds, while the over-under is set at 50.5. Before you make any 49ers vs. Rams picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on its top-rated NFL picks since its inception four years ago. It has nailed its recent top-rated NFL picks, entering Week 6 of the 2019 NFL schedule on a strong 23-14 run that dates back to last season. It's also on an 85-57 roll on top-rated NFL picks that dates back to the 2017 season. And in Week 5, it nailed the Rams (+1.5) staying within the spread against the Seahawks and the Texans (-4) covering with plenty of room to spare against the Falcons. The model also ranked in the Top 10 on NFLPickWatch for the third year in a row on straight-up NFL picks and beat more than 96 percent of CBS Sports office pool players. Anyone who has followed it is way up.

Now, it has simulated Rams vs. 49ers 10,000 times and the results are in. We can tell you that the model is leaning over, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

The model has taken into account that the Rams lost their second straight game last week, falling to the Seattle Seahawks 30-29. Russell Wilson thew four touchdown passes, including the game-winner with 2:28 to play. Rams quarterback Jared Goff completed 29-of-49 passes for 395 yards and one touchdown against one interception. Goff has passed for 1,649 yards and seven touchdowns, with wide receiver Cooper Kupp catching 41 passes for 505 yards and a touchdown. However, the Rams will be without running back Todd Gurley (quad) on Sunday against San Francisco. 

The 49ers, meanwhile, remained unbeaten last week by thumping the Cleveland Browns 31-3 on Monday Night Football. Running back Matt Breida had 11 carries for 114 yards and a touchdown in the victory, highlighted by an 83-yard scoring romp in the first quarter. For the season, quarterback Jimmy Garoppolo has passed for 920 yards and seven touchdowns. Additionally, the 49ers lead the NFL with 200 rushing yards per game and enter Sunday's showdown ranked second in the league in scoring offense, averaging 31.8 points per game.

So who wins 49ers vs. Rams? And which side of the spread cashes in over 50 percent of simulations? Visit SportsLine right now to see which side of the 49ers vs. Rams spread you need to jump on, all from the computer model that has crushed its NFL picks.