Week 11 will end with an NFC matchup between the New York Giants (3-6) and Tampa Bay Buccaneers (6-3) on Monday Night Football. The Giants are at the bottom of the NFC East standings, but have won two of their last three games to gain momentum. The Buccaneers have long been frontrunners in the NFC South, but consecutive losses have allowed other teams in their division to climb into the NFL playoff picture. Can the reigning champs assert themselves on their home turf to get back on track?

Kickoff is set for 8:15 p.m. ET. Tampa Bay is favored by 11 points in the latest Buccaneers vs. Giants odds from Caesars Sportsbook, while the Over-Under is 50. Before locking in your Giants vs. Buccaneers picks, make sure you check out the NFL predictions and betting advice from the SportsLine Projection Model

The model, which simulates every NFL game 10,000 times, is up almost $7,500 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 11 of the 2021 season on an incredible 128-89 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated Giants vs. Buccaneers 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model's Monday Night Football picks. Here are several NFL odds and betting lines for Giants vs. Buccaneers:

  • Buccaneers vs. Giants spread: Buccaneers -11 
  • Buccaneers vs. Giants over-under: 50 points  
  • Buccaneers vs. Giants money line: Tampa Bay -550, New York +400  
  • NYG: The Giants are 5-0 ATS in their previous five road games against the Buccaneers 
  • TB: The Buccaneers are 5-0 straight up in their last five home games
Featured Game | Tampa Bay Buccaneers vs. New York Giants

Why the Giants can cover

Only the Green Bay Packers can match the Buccaneers' unbeaten streak at home. Tampa Bay is 4-0 straight up and 3-1 against the spread at Raymond James Stadium. They've won by wide margins in three straight home contests since failing to cover against the Dallas Cowboys in Week 1.

The Cowboys' star receiving corps gave them a fighting chance against the Buccaneers, but the Giants lack the same offensive firepower. New York has a bottom 10 rushing attack, while its passing game has struggled without a true WR1. Tampa Bay doesn't have that problem, as it ranks third in points per game (31), first in passing yards per game (315.6), and first in passing touchdowns (27). The Buccaneers have won their home games by an average of 22 points and have only failed to win one home game by double-digits.

Why the Buccaneers can cover

Tampa Bay's last two losses have come away from Raymond James Stadium, but the Bucs have been one of the NFL's best teams at home. They're 4-0 straight up and 3-1 against the spread as hosts in 2021. They could build on their impressive run at home on Monday Night Football.

The Buccaneers have won three straight home games by double-digits since edging out the Cowboys by two points in the season-opener. Tampa Bay has won its last three home games by an average of 28.6 points, and its success has depended on a dynamic passing attack. The Bucs boast league-high marks in passing yards per game (315.6) and passing touchdowns (27), but the Giants don't have the same firepower and struggle to run the ball.

How to make Giants vs. Buccaneers picks 

SportsLine's model is leaning over the total, projecting the teams to combine for 50 points. The model also says one side of the spread cashes in well over 50 percent of simulations. You can only see the model's Giants vs. Buccaneers picks at SportsLine

So who wins Giants vs. Buccaneers on Monday Night Football? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to see which side of the Giants vs. Buccaneers spread to jump on, all from the advanced model that is up almost $7,500 on its NFL picks, and find out.