An NFC West clash is set for Sunday as Geno Smith, D.K. Metcalf and the Seattle Seahawks (2-3) host Kyler Murray and the Arizona Cardinals (2-3). Arizona lost in its bid to hand the Eagles their first loss of the season in Week 5, falling 20-17. Meanwhile, the Seahawks engaged in a shootout with the Saints but came up on the losing end, 39-32. The all-time series is virtually even through 46 games, with Seattle having 23 wins, Arizona having 22 victories, and there being one tie.
Kickoff from Lumen Field is set for 4:05 p.m. ET. Arizona is favored by 2.5 points in the latest Seahawks vs. Cardinals odds from Caesars Sportsbook, and the over/under is set at 50.5. Before entering any Cardinals vs. Seahawks picks, you'll want to see the NFL predictions from the model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2022 NFL season on an incredible 146-106 run on top-rated NFL picks that dates back to the 2017 season.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on Seahawks vs. Cardinals. You can head to SportsLine to see its picks. Here are several NFL betting lines for Cardinals vs. Seahawks:
- Seahawks vs. Cardinals spread: Cardinals -2.5
- Seahawks vs. Cardinals over/under: 50.5 points
- Seahawks vs. Cardinals picks: See picks here
What you need to know about the Seahawks
The Seahawks came within a touchdown against the New Orleans Saints this past Sunday, but they wound up with a 39-32 loss. Seattle's loss shouldn't obscure the performances of QB Geno Smith, who passed for three TDs and 268 yards, and WR Tyler Lockett, who caught five passes for two TDs and 104 yards. Near the top of the highlight reel was Smith's 50-yard TD bomb to WR DK Metcalf in the first quarter.
Seattle leads the NFL with 5.5 yards per carry but the team lost starting RB Rashaad Penny (leg) for the season versus the Saints. That thrusts second-round rookie Kenneth Walker III into the starting lineup and he impressed last week, rushing for 88 yards and a touchdown on just eight carries. But as good as Seattle has been on the ground, it has been equally as bad defending the run as the team has allowed the most rushing yards in the league.
What you need to know about the Cardinals
Meanwhile, the Cardinals fell 20-17 to the Philadelphia Eagles this past Sunday. No one had a standout game offensively for Arizona, but it got scores from RB Eno Benjamin and WR Marquise Brown. QB Kyler Murray accounted for 292 total yards but has failed to post a passer rating of at least 100 in any game this season.
Very few teams protect the ball as well as Arizona as it has just three turnovers this season, the third-fewest in the league. That is despite Murray leading the league with 215 pass attempts as he's throwing the ball nine more times per game this year than last. He may be called upon even more on Sunday as running back James Conner (ribs) and backup Darrel Williams (knee) have already been ruled out.
How to make Seahawks vs. Cardinals picks
The model has simulated Cardinals vs. Seahawks 10,000 times and the results are in. The model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.
So who wins Seahawks vs. Cardinals? And which side of the spread hits well over 50% of the time? Visit SportsLine right now to find out which side of the Cardinals vs. Seahawks spread you should be all over, all from the model on a 146-106 roll on its top-rated NFL picks, and find out.
