USATSI

The New York Giants have been offensively challenged all season and things have only gotten tougher with Daniel Jones suffering a torn ACL last week in a loss to the Raiders. In Week 10, the Giants will head to Dallas to take on the Cowboys, who soundly defeated New York 40-0 during the opening week of the season. The Cowboys are rolling offensively, with Dak Prescott throwing for 678 yards and seven touchdowns over the last two weeks.

Kickoff is at 4:25 p.m. ET. For this game, SportsLine consensus lists Dallas as the 17.5-point favorite, while the over/under is 39 points in the latest Giants vs. Cowboys odds. Before making any Cowboys vs. Giants picks, you need to see the NFL predictions and betting advice from the computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 of the 2023 NFL season on an incredible 174-123 run on top-rated NFL picks that dates back to the 2017 season. It also is on a 28-15 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Cowboys vs. Giants and just locked in its picks and NFL Week 10 predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for Giants vs. Cowboys:

  • Giants vs. Cowboys spread: Cowboys -17.5
  • Giants vs. Cowboys over/under: 39 points
  • Giants vs. Cowboys money line: Cowboys -2111, Giants +1054
  • Giants vs. Cowboys picks: See picks at SportsLine
  • Giants vs. Cowboys live stream: fubo (try for free)

Why the Giants can cover

The Cowboys are strong defensively, but they have shown signs of vulnerability against the run in 2023. Dallas allows an average of 108.9 rushing yards per game, and the Giants have one of the NFL's best running backs in Saquon Barkley. The two-time Pro Bowl selection enters Sunday with 502 rushing yards and one touchdown, and 22 receptions for 110 yards to two touchdown catches.

The Giants also have a budding star on the defensive side of the ball in outside linebacker Kayvon Thibodeaux. The former first round pick out of Oregon has already racked up 8.5 sacks through nine games in his second professional season. With Dallas' offensive line injury concerns, Thibodeaux could be in for a big day. See which team to pick here.

Why the Cowboys can cover

Dallas absolutely dominated defensively in a Week 1 matchup against the Giants, sacking Jones seven times and forcing three turnovers while allowing only 171 yards of total offense in a shutout victory. Now the Giants will have undrafted rookie Tommy DeVito under center and he'll be without top tight end Darren Waller, who is on injured reserve with a hamstring injury.

That should allow for a Cowboys defense that ranks sixth in points allowed and third in yards allowed to focus their efforts on stopping running back Saquon Barkley. In four games since returning from a high-ankle sprain, Barkley has carried the ball 97 times for 388 yards but he'll have his work cut out against a Cowboys defense that has only allowed 254 rushing yards in their last three games. See which team to pick here.

How to make Giants vs. Cowboys picks

The model has simulated Giants vs. Cowboys 10,000 times and the results are in. It is leaning Over on the point total, and it also says one side of the spread hits in well over 50% of simulations. You can only see the model's Cowboys vs. Giants pick at SportsLine.

So who wins Cowboys vs. Giants, and which side of the spread hits well over 50% of the time? Visit SportsLine right now to see which side of the Giants vs. Cowboys spread you should be all over Sunday, all from the model on a 174-123 roll on its top-rated NFL picks, and find out.