The Green Bay Packers will return home for Monday Night Football after a long stretch away from Lambeau Field. The Packers will host the Los Angeles Rams in the finale of Week 15, the first home tilt for Green Bay since Nov. 17. The Packers are 5-8 overall and 3-3 at home this season, with a 2-2 mark in the last four games. The Rams stopped a six-game losing streak with a win last week and Los Angeles is 4-9 overall.

Kick-off is at 8:15 p.m. ET in Green Bay. Caesars Sportsbook lists the Packers as 7.5-point home favorites, while the over/under, or total number of points Vegas thinks will be scored, is 40.5 in the latest Rams vs. Packers odds. Before you make any Packers vs. Rams picks, you need to see the NFL predictions and betting advice from SportsLine's advanced computer simulation model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 15 of the 2022 NFL season on an incredible 157-113 run on top-rated NFL picks that dates back to the 2017 season. The model is also a sizzling 21-5 on straight-up NFL picks over the past two weeks. 

The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Rams vs. Packers and just locked in its picks and NFL predictions. You can head to SportsLine now to see the model's picks. Now, here are several NFL odds and betting lines for Rams vs. Packers:

  • Rams vs. Packers spread: Packers -7.5
  • Rams vs. Packers over/under: 40.5 points 
  • Rams vs. Packers money line: Packers -365, Rams +285
  • LAR: Rams are 4-7-2 against the spread this season 
  • GB: Packers are 5-8 against the spread this season 
  • Rams vs. Packers picks: See picks here
Featured Game | Green Bay Packers vs. Los Angeles Rams

Why the Rams can cover

Los Angeles boasts the NFL's second-best fourth down efficiency, but Los Angeles is better on defense. The Rams are yielding only 330.5 total yards per game this season, and the team's rushing defense is elite. Opponents are averaging only 101.9 rushing yards per game and 4.0 yards per carry against the Rams, landing Los Angeles in the top five in both categories.

The Rams have given up only eight rushing touchdowns all season, and Los Angeles is giving up only 18.6 first downs per game. The Rams can also play a bend-but-don't-break approach with the NFL's No. 2 mark in red zone efficiency on defense, allowing opponents to score touchdowns on only 41.5% of trips inside the 20-yard line. See which team to pick here.

Why the Packers can cover

Green Bay is in the top five in passing defense, giving up only 192.9 yards per game through the air, and the Packers have yielded only 18 touchdown passes against 10 interceptions in 2022. The Packers also have a 38.2% third down efficiency, allowing Green Bay to get off the field consistently.

The Rams are No. 29 in scoring (16.8 points per game) and No. 31 in total yards (283 per game). Los Angeles is No. 27 in first downs, No. 25 in passing yards, No. 31 in net yards per pass attempt, No. 30 in rushing yards, and No. 31 in yards per carry. See which team to pick here.

How to make Rams vs. Packers picks

SportsLine's model is leaning Over on the point total, with a modest line and both teams projected to throw for more than 220 yards. The model also says one side of the spread hits in well over 50% of simulations. You can only see the model's MNF picks at SportsLine.

So who wins Packers vs. Rams on Monday Night Football? And which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the Packers vs. Rams spread you need to jump on Monday, all from the model that has crushed its NFL picks, and find out.