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The Xavier Musketeers will take on the Vanderbilt Commodores at 9 p.m. ET on Tuesday at the Cintas Center in the quarterfinals of the 2022 National Invitation Tournament. Xavier is 20-13 overall and 15-5 at home, while Vanderbilt is 19-16 overall and 5-7 on the road. The second-seeded Musketeers and the fourth-seeded Commodores are both trying to book their spot in the semifinals of the 2022 NIT. 

The Musketeers are favored by 2.5 points in the latest Xavier vs. Vanderbilt odds from Caesars Sportsbook, while the over-under is set at 142.5. Before entering any Vanderbilt vs. Xavier picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $1,300 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Xavier vs. Vanderbilt in the NIT 2022. You can head to SportsLine to see its picks. Here are several college basketball odds for Vanderbilt vs. Xavier:

  • Xavier vs. Vanderbilt spread: Xavier -2.5
  • Xavier vs. Vanderbilt over-under: 143.5 points
Featured Game | Xavier Musketeers vs. Vanderbilt Commodores

What you need to know about Xavier

Xavier looked like a lock to make the NCAA Tournament when it got off to a 16-5 start this season, but the Musketeers only won two games in the final month of the regular season. Their hopes of making the Big Dance were slashed in an overtime loss to Butler in the Big East Tournament. They have made the most of their opportunity in the NIT, however, picking up wins over Cleveland State and Florida

The Musketeers took the lead three minutes into their game against Florida and never trailed again. Junior forward Jack Nunge leads the team with 13.4 points and 7.4 rebounds per game. Second-leading scorer Paul Scruggs left the game against Florida with a knee injury and is questionable to play on Tuesday night. 

What you need to know about Vanderbilt

Vanderbilt struggled at times during conference play, but the Commodores have taken another step in the rebuilding process. They picked up a pair of wins in the SEC Tournament and have opened the NIT with victories over Belmont and Dayton. Vanderbilt can record its first 20-win season since 2014-15 with a win on Tuesday night. 

Center Liam Robbins had not practiced due to an ankle injury, but he came up with a clutch block and bucket in the win over top-seeded Dayton in overtime on Sunday. Junior guard Scotty Pippen Jr. leads Vanderbilt with 20.2 points, 4.2 assists and 3.4 rebounds per game. The Commodores have covered the spread in five straight games as underdogs. 

How to make Xavier vs. Vanderbilt picks

The model is leaning under on the total, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Vanderbilt vs. Xavier? And which side covers almost 60 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its college basketball picks.