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Pittman (knee) departed Wednesday's practice early after appearing to injure his knee during a collision in 11-on-11 drills, James Boyd of The Athletic reports.

Pittman was examined by trainers before limping off the field, and it appears safe to say that his on-field activities for Wednesday's session are over. The Colts should provide an update on Pittman's health soon, as he's entrenched as the focal point of the passing game after signing a three-year, $70 million contract earlier this offseason. In the meantime, second-year quarterback Anthony Richardson will be able to focus on developing chemistry with Josh Downs, rookie second-round pick Adonai Mitchell and Alec Pierce.

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