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Despite no running backs going in the first round of this year's draft, the position still has a strong rookie class. Dameon Pierce and Kenneth Walker III are at the top of the pile, but others like Tyler Allgeier and Brian Robinson Jr. have emerged in recent weeks. With the 2022 NFL season in the midst of bye weeks, Fantasy football rookies have steadily risen in the Week 10 Fantasy football rankings. Even seventh-rounder Isiah Pacheco has entered the conversation as a Week 10 Fantasy football start-sit decision after his snaps have increased in three straight games. He's also had more touches than Clyde Edwards-Helaire the last two weeks for the Chiefs. Is Pacheco worth a start against a soft Jaguars defense on Sunday? Before locking in your Week 10 Fantasy football lineups, be sure to check out the Week 10 Fantasy football rankings from the proven computer model at SportsLine.

When it comes to ranking players, SportsLine's model beat human experts in Fantasy football for the past several seasons especially when there were big differences in ranking. Over the course of a season, that could literally be the difference between winning your league or going home empty-handed.

Last week, the model was extremely high on Jaguars running back Travis Etienne, saying he'd finish as a top-10 player at his position. The result: Etienne recorded 28 carries for 109 yards and two touchdowns in Sunday's win over the Raiders. Anybody who had him in their lineup was well on their way to a huge week.

Now, the model, which simulates every NFL game 10,000 times, has revealed its Fantasy football rankings for Week 10 of the 2022 NFL season. Head to SportsLine now to see them.

Top Week 10 Fantasy football picks  

One player the model is high on this week: Giants quarterback Daniel Jones. He has quietly averaged the 14th-most Fantasy points at the QB position since Week 4, even besting the likes of Lamar Jackson and Justin Herbert. Jones' passing numbers may not jump off the page, but he's one of the most effective running quarterbacks in the game. He's averaged over 50 rushing yards over his last six contests and ranks fourth among QBs in rushing this season.

With top QBs like Jackson and Joe Burrow on bye this week, Jones is a bonafide QB1 for Week 10. He gets a dream matchup against the Texans, who rank 30th in yards allowed, and Houston struggled with another mobile quarterback last week. Jalen Hurts had 243 passing yards, 23 rushing yards, two total TDs and a two-point conversion versus the Texans. Jones is a top-10 QB in the model's Week 10 Fantasy football QB rankings, so you should have no qualms about utilizing him as your starter. See who else to target here.

And a massive shocker: Chargers quarterback Justin Herbert, who's thrown for 2,254 yards and 13 touchdowns this season, stumbles big-time and doesn't even crack the top 10 at his position.

Herbert's 2,254 passing yards rank fifth in the league, but he's failed to throw more than one touchdown in three of his last four games. Plus, Herbert and the Chargers square off against the San Francisco 49ers on Sunday, a defense that's giving up just 285.9 yards per game this season, which ranks first in the NFL. With such a tough matchup on Sunday, Herbert is a player to consider putting on the bench in Week 10. See who else to fade here.

How to set Week 10 Fantasy football rankings

The model is also calling for a surprising quarterback you aren't even thinking about to finish in the top 10 of its Week 10 Fantasy football rankings. This pick could be the difference between winning big and going home with nothing. You can only see who it is here.

So who should you start and sit this week? And which surprising quarterback could lead you to victory? Visit SportsLine now to get Week 10 Fantasy football rankings for every position, plus see which QB is going to come out of nowhere to crack the top 10, all from the model that has outperformed experts big-time.