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I wanted to be optimistic about DeAndre Hopkins after Monday's game where he had 12 targets, but he is set to undergo season-ending knee surgery, putting him out for the regular season and in doubt for the NFL playoffs at this point. That's a disappointing end to Hopkins' Fantasy season, but does it open up the possibility for someone else in this offense to step up? Or possibly two someone elses?

Unfortunately, the games that Hopkins missed earlier this season probably won't tell us much, because they all overlapped with Kyler Murray's absence. Christian Kirk had 18 targets and Rondale Moore had 20 in those three games, while A.J. Green had 11 in two of them; Zach Ertz had 20. So, the Cardinals still spread it around a ton, which has been their M.O. whether it's been Murray or Colt McCoy in at QB. And I do expect that to continue to be the case, which makes it hard to trust any of them. 

I'm willing to move Green and Kirk into the WR3/4 range for Week 14 against the Lions, and Moore's usage in both the running game and passing game continue to make him an intriguing player, but I'll need to see more from him before I use him. The problem is, it's not like the Cardinals were really using Hopkins as a true No. 1 receiver anyways, as his 21% target share was his lowest since his rookie season. So, it's hard to see why Green or Hopkins or Moore would step into a significantly larger role suddenly. 

Here are my top 48 wide receivers for Week 15. To see the rankings from Jamey Eisenberg, Dave Richard and Heath Cummings, make sure you head here

Injury report

As you can tell, it's kind of a mess this week. The Monday and Tuesday games have some big names whose status is completely up in the air, and if you've got to make the decision right now, you probably can't take the risk on Lockett, Thielen, or Landry; I'm a bit more optimistic about McLaurin because he was able to practice in full Saturday, however with the top two QBs on the roster still in doubt, he's probably not worth the risk either, unless you can pivot to someone like Van Jefferson or DeVonta Smith

One bit of good news we got from those delayed games is that Odell Beckham was activated off the COVID list, so he should be good to go. I'm viewing him as more of a low-end WR2 with upside, with Van Jefferson ranking just behind him. I rank D.J. Moore in the same range, while Marquise Brown is a bit lower -- he'd be in that range if Lamar Jackson were to play, however. 

Week 15 WR Rankings

  1. Davante Adams @BAL
  2. Cooper Kupp vs. SEA
  3. Justin Jefferson @CHI
  4. Stefon Diggs vs. CAR
  5. Chris Godwin vs. NO
  6. Diontae Johnson vs. TEN
  7. Deebo Samuel vs. ATL
  8. Hunter Renfrow @CLE
  9. CeeDee Lamb @NYG
  10. Ja'Marr Chase @DEN
  11. Tee Higgins @DEN
  12. Mike Evans vs. NO
  13. Brandin Cooks @JAX
  14. Amari Cooper @NYG
  15. D.K. Metcalf @LAR
  16. DeVante Parker vs. NYJ
  17. D.J. Moore @BUF
  18. Chase Claypool vs. TEN
  19. Russell Gage @SF
  20. Odell Beckham vs. SEA
  21. Brandon Aiyuk vs. ATL
  22. Van Jefferson vs. SEA
  23. Julio Jones @PIT
  24. Terry McLaurin @PHI
  25. Amon-Ra St. Brown vs. ARI
  26. DeVonta Smith vs. WAS
  27. Marquise Brown vs. GB
  28. Gabriel Davis vs. CAR
  29. Jerry Jeudy vs. CIN
  30. A.J. Green @DET
  31. Michael Gallup @NYG
  32. Cole Beasley vs. CAR
  33. Jakobi Meyers @IND
  34. K.J. Osborn @CHI
  35. Jamison Crowder @MIA
  36. Darnell Mooney vs. MIN
  37. Laviska Shenault vs. HOU
  38. Marvin Jones vs. HOU
  39. Sterling Shepard vs. DAL
  40. Christian Kirk @DET
  41. Tyler Boyd @DEN
  42. Rashod Bateman vs. GB
  43. Kenny Golladay vs. DAL
  44. Adam Humphries @PHI
  45. Nico Collins @JAX
  46. Tim Patrick vs. CIN
  47. Donovan Peoples-Jones vs. LV

So who should you start and sit this week? And which surprising quarterback could lead you to victory? Visit SportsLine now to get Week 15 rankings for every position, plus see which QB is going to come out of nowhere to crack the top 10, all from the model that has out-performed experts big-time.