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The Tampa Bay Rays kicked off their last road trip with a season-best five-game winning streak that put them over .500 for the first time since the first week of the year. They're hoping to achieve similar success after enduring a 4-6 homestand during which they scored fewer than three runs on six occasions. Should you expect the Rays to resume their winning ways on the road, or is there value in the Los Angeles Angels to hand Tampa Bay its fourth loss in five contests and bring a return on the money line?

The latest MLB odds for Monday from WIlliam Hill Sportsbook list the Rays at -115 (risk $115 to win $100) against the Angels. Other MLB lines of note include the San Diego Padres at -180 against the Pittsburgh Pirates and the Oakland Athletics listed as slight money-line favorites (-115) versus the Toronto Blue Jays. Before making any MLB picks or predictions on those games or others, you need to see the MLB predictions and betting advice from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line MLB picks. It is off to a profitable start in 2021, going 29-21 on top-rated MLB money-line picks through four weeks, returning over $250. Anyone following it has seen huge rewards.

Now, the model has crunched the numbers for the Monday MLB schedule and posted its best bets for the evening games. Parlaying these four MLB picks would pay almost 12-1. Head to SportsLine to see the picks

Top MLB picks for Monday, May 3

The model likes the San Francisco Giants at +110 on the money line against the Colorado Rockies. The Giants have dominated the season series thus far, winning five of six contests at home. San Francisco hasn't had much trouble producing runs against Colorado, outscoring the Rockies 11-4 during a three-game sweep in early April before crossing the plate 24 times while winning two of three last week. 

The Giants are hoping for a solid performance from Aaron Sanchez, who has allowed two runs or fewer in each of his five starts this year after missing 2020 with a shoulder injury.

San Francisco is looking to again get the better of German Marquez, who is 0-2 with a 6.52 ERA in two starts against the Giants this year. The 26-year-old Venezuelan righty surrendered seven runs over 9 ⅔ innings in those outings and is 4-6 with a 5.67 ERA in 12 career turns versus San Francisco. Brandon Belt has enjoyed success against Marquez during his career, going 11-for-27 with a home run and six RBIs.

Featured Game | Colorado Rockies vs. San Francisco Giants

How to make MLB predictions, parlays for Monday, May 3

The model has locked in three other MLB best bets, including another strong underdog play that returns plus money. You can see the best bets only at SportsLine.

So which MLB picks should you make on Monday for a shot at a big return of almost 12-1? And which underdog do you need to be all over? Visit SportsLine now to see Monday's MLB picks, all from the projection model off to a fast start in 2021, and find out.