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The Cleveland Cavaliers will take on the Charlotte Hornets at 7 p.m. ET on Friday at Rocket Mortgage FieldHouse. The Cavaliers lost their season opener to the Grizzlies on Wednesday, 132-121. The Hornets beat the Pacers in their opener, 123-122. 

The Cavaliers won two of the three meetings between the teams last season. Charlotte is favored by 2.5-points in the latest Cavaliers vs. Hornets odds from Caesars Sportsbook, and the over-under is set at 225.5. Before entering any Hornets vs. Cavaliers picks, you'll want to see the NBA predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned almost $9,000 in profit on its top-rated NBA picks over the past three seasons. The model finished up almost $600 on its top-rated picks last season and enters the 2021-22 NBA season on a stunning 100-66 roll on top-rated NBA picks against the spread. Anyone following it has seen huge returns.

Now, the model has set its sights on Cavaliers vs. Hornets. You can head to SportsLine to see its picks. Here are several NBA betting lines for Cavaliers vs. Hornets:

  • Cavaliers vs. Hornets spread: Cavaliers +2.5
  • Cavaliers vs. Hornets over-under: 225.5 points
Featured Game | Cleveland Cavaliers vs. Charlotte Hornets

What you need to know about the Hornets

P.J. Washington's pair of free throws with 4.6 seconds remaining wrapped up Charlotte's win over Indiana. The Hornets overcame a 75-59 halftime deficit and went on a 24-0 run in the third quarter. LaMelo Ball shot 7-for-9 from beyond the arc and finished with 31 points, seven assists and nine rebounds. He scored 12 of the team's 24 points during the third quarter surge. 

Gordon Hayward scored 27 points vs. the Pacers. Mason Plumlee had 10 rebounds in his first game with the Hornets. Terry Rozier (ankle) did not play on Wednesday and is listed as questionable for Friday's game. 

What you need to know about the Cavaliers

In the loss to Memphis, Jarrett Allen scored 25 points as he made all 11 of his field goal attempts. He became the first NBA player in the shot clock era to hit at least all 10 of his field goal attempts in a season opener. It was the second time in his career that he went 11-for-11 from the field. Evan Mobley had 17 points and nine rebounds in his pro debut. 

Cleveland has won 27 of its last 33 home games vs. Charlotte. Darius Garland (ankle) is questionable for Friday's game. He had 13 points and 12 assists on Wednesday. 

How to make Hornets vs. Cavaliers picks

The model has simulated Cavaliers vs. Hornets 10,000 times and the results are in. We can tell you that the model is leaning under, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Cavaliers vs. Hornets? And which side of the spread hits in nearly 60 percent of simulations? Visit SportsLine now to find out which side of the Cavaliers vs. Hornets spread you need to jump on Friday, all from the model that has crushed its NBA picks, and find out.