The Denver Broncos (3-3) will visit the Cleveland Browns (3-3) on Thursday Night Football in Week 7. The Browns were blown out at home by the Arizona Cardinals last Sunday, while the Broncos were also embarrassed at home by the Las Vegas Raiders. Denver is on a three-game losing streak, dropping to third in the AFC West, while the Cleveland Browns fell to third in the AFC North with their second consecutive loss. Thursday Night Football is crucial for both teams as they look to end losing streaks, but the Browns will be without quarterback Baker Mayfield (shoulder) and star running backs Nick Chubb (calf) and Kareem Hunt (calf).

Kickoff from FirstEnergy Stadium is set for 8:20 p.m. ET. Cleveland is favored by 1.5 points in the latest Broncos vs. Browns odds from Caesars Sportsbook, while the Over-Under is 40.5. Before locking in any Browns vs. Broncos picks, you need to check out the NFL predictions and analysis from the proven SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up almost $7,700 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 7 of the 2021 season on an incredible 125-85 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated Browns vs. Broncos 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model's picks. Now, here are several NFL odds and betting lines for Browns vs. Broncos:

  • Broncos vs. Browns spread: Browns -1.5
  • Broncos vs. Browns over-under: 40.5 points 
  • Broncos vs. Browns money line: Cleveland -125, Denver +105
  • CLE: Browns are 7-3 ATS in their last 10 Thursday games  
  • DEN: Over is 4-1 in Broncos' last five games following a straight-up loss  

Why the Browns can cover

The Broncos' defense has been stout through six games, allowing 314.7 total yards per contest. Von Miller missed the entire 2020 season with an ankle injury but has rebounded in 2021. Miller has 17 total tackles, including eight solo. He also has seven tackles for loss with 4.5 sacks.

The tandem at safety for Denver has also played extremely well. Kareem Jackson leads the Broncos with 34 total tackles, including 23 solo. Jackson has also sacked the quarterback once and recorded an interception. Justin Simmons is third in total tackles with 28 and has three pass deflections and one interception.

Why the Broncos can cover

Wide receiver Tim Patrick has stepped up in the absence of fellow receiver Jerry Jeudy. The latter suffered a high-ankle sprain in Week 1 that caused him to miss the past five games. Patrick is second on the team with 344 yards on 25 receptions with three touchdowns. He is also second on the team with 57.3 yards per game while reeling in 13.8 yards per reception.

Tight end Noah Fant has also made plays for the Broncos. Fant is an athletic tight end who can make defenders miss in open space. The Iowa product has hauled in 30 passes for 273 yards with three touchdowns. Three of Fant's receptions have gone for 20-plus yards. He is coming off his best game of the season against the Raiders in which he caught nine passes for 97 yards and a score.

How to make Broncos vs. Browns picks 

SportsLine's model is leaning over on the point total, projecting the teams to combine for 44 points. The model also says one side of the spread hits well over 50 percent of the time. You can only see the model's Broncos vs. Browns picks at SportsLine.

So who wins Browns vs. Broncos on Thursday Night Football? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to see which side of the Browns vs. Broncos spread to jump on, all from the advanced model that is up almost $7,700 on its NFL picks, and find out.