The New York Jets (2-5) and the Indianapolis Colts (3-5) will duel it out in a primetime matchup on Thursday Night Football. It's the first game of the Week 9 NFL schedule. The Jets will try to pull off back-to-back upsets when they travel to Lucas Oil Stadium. New York beat the Cincinnati Bengals in a thrilling Week 8 matchup. In Week 3 last season, the Colts blew out the Jets, 36-7. Indianapolis hopes it will be a similar outcome on Thursday Night Football.

Kickoff from Lucas Oil Stadium is set for 8:20 p.m. ET. Indianapolis is favored by 10 points in the latest Jets vs. Colts odds from Caesars Sportsbook, while the Over-Under is 45. Before locking in your Colts vs. Jets picks, make sure you check out the NFL predictions and betting advice from the red-hot SportsLine Projection Model

The model, which simulates every NFL game 10,000 times, is up almost $7,800 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 9 of the 2021 season on an incredible 128-86 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the Top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up!

Now, the model has simulated Jets vs. Colts 10,000 times and just revealed its coveted NFL picks and TNF predictions. You can head to SportsLine now to see its picks. Now, here are several NFL odds and Thursday Night Football betting lines for Colts vs. Jets:

  • Jets vs. Colts spread: Colts -10
  • Jets vs. Colts over-under: 45 points 
  • Jets vs. Colts money line: Colts -550, Jets +400 
  • IND: Colts are 5-3 against the spread 
  • NYJ: Over is 4-0 in Jets' last four games as underdogs

Why the Colts can cover

In each win this season, the Colts have been able to successfully mix in the run and the pass. In those matchups, Jonathan Taylor rushed for over 100 yards, while Carson Wentz threw at least two passing touchdowns with no interceptions. Wentz went 52-of-78 for 601 yards with six passing touchdowns in those victories.

Michael Pittman Jr. has emerged as the No. 1 receiver for Indianapolis. Wentz and Pittman Jr. have developed a strong rapport through the first eight games of the year. The USC product ranks ninth in the league with 594 receiving yards. Pittman Jr. has caught eight passes for 20-plus yards and averages a team-high 74.3 receiving yards per game.

Why the Jets can cover

New York's offense exploded against the Cincinnati Bengals. The Jets finished with a season-high 511 total yards of offense with 6.6 yards per play. Quarterback Mike White started his first career game since rookie Zach Wilson was out with a knee injury. White went 37-of-45 for 405 yards and three touchdowns.

Rookie running back Michael Carter had his best game as a pro, posting 15 carries for 77 yards with a score and also adding nine catches for 95 yards. The shifty tailback made defenders miss in the open field and was a safety valve for White. New York was down 11 points with five minutes remaining in the fourth quarter, but showed plenty of resilience in its comeback victory. The Jets hope to carry this momentum into Thursday Night Football.

How to make Jets vs. Colts picks

SportsLine's model is leaning over the total, projecting the teams to combine for 47 points. The model also says one side of the spread hits in almost 60 percent of simulations. You can only see the model's Jets vs. Colts picks at SportsLine

So who wins Colts vs. Jets on Thursday Night Football? And which side of the spread hits in almost 60 percent of simulations? Visit SportsLine now to see which side of the Colts vs. Jets spread to jump on, all from the advanced model that is up over $7,900 on its NFL picks, and find out.