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The Carolina Panthers (2-12) are fresh off a victory and looking to build some momentum to finish out the season. They'll host the Green Bay Packers (6-8) on Sunday, a team that's coming off back-to-back losses. The Packers have won eight of the last 12 meetings against the Panthers. 

Kickoff in Charlotte is scheduled for 1 p.m. ET. The Packers are favored by 4 points in the latest Panthers vs. Packers odds, and the over/under is 38.5 points. Before locking in any Panthers vs. Packers picks, you'll want to see the NFL predictions and betting advice from the proven computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 16 of the 2023 NFL season on an incredible 178-129 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 32-21 roll on top-rated NFL picks since Week 7 of last season. 

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

The model has set its sights on Packers vs. Panthers and just locked in its picks and NFL predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for the game:

  • Panthers vs. Packers spread: Packers -4
  • Panthers vs. Packers over/under: 38.5 points
  • Panthers vs. Packers money line: Packers -208, Panthers +172
  • Panthers vs. Packers picks: See picks here
  • Panthers vs. Packers live stream: fubo (try for free)

What you need to know about the Packers

Green Bay is coming off disappointing back-to-back losses against the Buccaneers and Giants that have put them in a difficult position in the NFC playoff hunt. However, Jordan Love continues to evolve into a more capable quarterback and his numbers over the last several weeks show that.

Over the last six weeks, Love has thrown for 1,648 yards and 13 touchdowns with only three interceptions. He's also completing 65.9% of his passes during that stretch after completing only 59.6% of his passes over his first eight starts of the season. Love and the Green Bay offense could pose some significant threats to a Carolina defense that ranks 29th in points allowed (24.9 points per game). See which team to pick here.

What you need to know about the Panthers

Meanwhile, Carolina had to suffer through a six-game losing streak, but that ended last week, escaping with a 9-7 victory over the Falcons on Sunday. The win was just what Carolina needed coming off of a 28-6 defeat in its prior matchup.

The Panthers have long been eliminated from postseason contention, but are looking to build some momentum heading into the offseason. Rookie quarterback Bryce Young has struggled, but he has gained valuable experience. Young enters this Week 16 matchup completing 59.4% of his passes for 2,359 yards, nine touchdowns and nine interceptions. Veteran wide receive Adam Thielen has had a nice bounce back year, with 89 catches for 870 yards and four touchdowns thus far. See which team to pick here.

How to make Panthers vs. Packers picks

The model has simulated Panthers vs. Packers 10,000 times and the results are in. The model is leaning Over on the point total, and it's also generated a point-spread pick that has all the value. You can only see the model's pick at SportsLine.

So who wins Packers vs. Panthers on Sunday and which side of the spread has all the value? Visit SportsLine now to see which side of the point spread you need to jump on, all from the model on a 178-129 roll on NFL picks, and find out.