Fresh off their Hall of Fame Game win over the Jacksonville Jaguars, the Las Vegas Raiders will open their preseason home slate against the Minnesota Vikings on Sunday. The Vikings will debut their new coaching staff, led by former Los Angeles Rams offensive coordinator Kevin O'Connell. Neither starting quarterback is expected to play, however. The Raiders' Derek Carr is expected to be a healthy scratch, while Vikings quarterback Kirk Cousins will be sidelined due to a COVID-19 positive test.

Kickoff from Allegiant Stadium in Las Vegas is set for 4:25 p.m. ET. Minnesota quarterback Kirk Cousins will miss the game after testing positive for COVID-19. Las Vegas is a four-point favorite in the latest Vikings vs. Raiders odds from Caesars Sportsbook, while the over-under for total points scored is 36. Before making any Raiders vs. Vikings picks or bets, be sure to check out the NFL predictions from SportsLine's R.J. White.

Over the past seven years White, a CBS Sports Fantasy and gambling editor, has gone 329-250-21 (56.8 percent) in the world's most prestigious football handicapping competition, the Las Vegas SuperContest. He also is SportsLine's No. 1 NFL expert, going 445-378-24 on his against-the-spread NFL picks from 2017-21, returning $2,542 to $100 players.

In addition, White is 41-21-3 on his last 65 against-the-spread picks involving the Vikings. Anyone who has followed him is way up.

Now, White has zeroed in on Raiders vs. Vikings and just locked in his NFL picks and predictions. You can head to SportsLine now to see his picks and analysis. Here are the NFL odds and betting lines for Vikings vs. Raiders:

  • Vikings vs. Raiders spread: Las Vegas -4
  • Vikings vs. Raiders over-under: 36 points
  • Vikings vs. Raiders money line: Minnesota +175, Las Vegas -210
  • MIN: Vikings went 0-3 last preseason and were outscored 73-41
  • LV: Raiders were 2-1 in the 2021 preseason, going 1-0 at home
  • Vikings vs. Raiders picks: See picks at SportsLine
Featured Game | Las Vegas Raiders vs. Minnesota Vikings

Why the Raiders can cover

Las Vegas solidified the top part of its wide receiver corps this offseason by acquiring Davante Adams from the Green Bay Packers. The Raiders, however, will use Sunday's game to take a look at the position's depth. Among those who saw action against Jacksonville was third-year pro Tyron Johnson, who played for Jacksonville in 2021 and the Los Angeles Chargers in 2020. In his first two seasons, Johnson has 22 receptions for 414 yards (18.8 average) and three touchdowns. Last week against the Jaguars, Johnson caught two passes for 39 yards.

Another receiver looking to solidify a roster spot is sixth-year pro DeMarcus Robinson, who played his first five seasons with the Kansas City Chiefs. Robinson played in all 17 games last season for the Chiefs, catching 25 passes for 264 yards (10.6 average) and three touchdowns. For his career, he has played in 81 games, catching 145 passes for 1,679 yards (11.6 average) and 14 touchdowns. Last week, he had two catches for 17 yards.

Why the Vikings can cover 

With Cousins down with COVID-19, look for backup quarterbacks Kellen Mond and Sean Mannion to see action. Both backups played in one game a year ago, with Mond completing 2-of-3 passes for five yards, while Mannion was 22-of-36 (61.1 percent) for 189 yards and a touchdown. Mannion is in his seventh season after being a third-round pick for the St. Louis Rams in 2015. He has one career touchdown and three picks. Mond was a third-round pick for Minnesota a year ago.

K.J. Osborn is expected to get work in as he tries to lock down the No. 3 wide receiver job and looks to impress new coach Kevin O'Connell. Osborn, a fifth-round selection by the Vikings in 2020, had a solid season a year ago. He finished with 50 receptions for 655 yards (13.1 average) and seven touchdowns.

How to make Vikings vs. Raiders picks

For Sunday's NFL preseason game, White is leaning Over the total, but he also says a critical X-factor makes one side of the spread a must-back. You can find out what it is and see all of White's NFL picks and analysis at SportsLine

Who wins Raiders vs. Vikings on Sunday? And which critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the Vikings vs. Raiders spread you need to jump on, all from the expert who is on a 41-21 run picking Minnesota against the spread, and find out.