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The New Orleans Saints look to win their third road game of 2023 as they face off against the Houston Texans on Sunday afternoon. New Orleans (3-2) crushed the Patriots, 34-0 in Week 5, while Houston (2-3) fell at the final whistle, 21-19 to Atlanta. The Saints' franchise is 0-2 lifetime at NRG Stadium and the home team is a perfect 5-0 lifetime in this series. New Orleans is 1-3-1 against the spread, while Houston is 3-2 ATS in 2023.

Kickoff at NRG Stadium in Houston is scheduled for 1 p.m. ET. New Orleans is favored by 1.5 points in the latest Texans vs. Saints odds, and the over/under for total points scored is 42.5. Before making any Saints vs. Texans picks, you need to see the NFL predictions and betting advice from the computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2023 NFL season on an incredible 171-119 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 25-11 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Texans vs. Saints and just locked in its picks and NFL Week 6 predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for Saints vs. Texans:

  • Saints vs. Texans spread: Saints -1.5
  • Saints vs. Texans over/under: 42.5 points
  • Saints vs. Texans money line: Saints -128, Texans +108
  • Saints vs. Texans picks: See picks at SportsLine
  • Saints vs. Texans live stream: fubo (try for free)

Why the Saints can cover

After struggling mightily and battling through a shoulder injury in Week 4's loss to Tampa Bay, Saints quarterback Derek Carr bounced back with a 183 yard, two touchdown performance against the Patriots on Sunday. Running back Alvin Kamara, in his second game back from suspension, rushed for 80 yards on 23 carries, while catching an additional three passes for 17 yards. Houston ranks in the bottom half of the NFL in rushing yards allowed (112.4), so Kamara's effectiveness could be key to securing a Saints victory.

New Orleans' defense also needs to slow down Houston's offense, as they did New England's last weekend. The Saints held Mac Jones and company to only 156 total yards and limited them to only 20 minutes and 26 seconds in time of possession. They forced three turnovers, including safety Tyrann Mathieu's 27-yard interception return to open the scoring. See which team to pick here.

Why the Texans can cover

Houston has been a pleasant surprise led by current Offensive Rookie of the Year favorite, QB C.J. Stroud. In their two victories this season, the Texans have scored 30 or more points in both games, which is an impressive feat considering they only did that once during the 2022 season. In his first five NFL games, Stroud has thrown for seven scores on 1,461 yards passing and no interceptions. He has opened his NFL career with zero interceptions on 186 attempts, which is an NFL record.

Another pleasant surprise has been Houston's receiving core, despite quiet Week 5 outings, led by veterans Nico Collins (3-39-0) and Robert Woods (3-30-0), as well as rookie Tank Dell (3-57-0). The team's leading receiver against Atlanta was tight end Dalton Schultz, who caught seven passes for 65 yards and a touchdown. New Orleans ranks fourth against the pass this season (183 yards per game), so Stroud and his receivers will likely have to surpass those numbers in order to keep pace with an improving Saints offense. See which team to pick here.

How to make Saints vs. Texans picks

The model has simulated Texans vs. Saints 10,000 times and the results are in. It is leaning Under on the point total, and it also says one side of the spread hits well over 50% of the time. You can only see the model's Saints vs. Texans pick at SportsLine.

So who wins Texans vs. Saints on Sunday, and which side of the spread hits well over 50% of the time? Visit SportsLine right now to see which side of the Saints vs. Texans spread you should be all over Sunday, all from the model on a 171-119 roll on its top-rated NFL picks, and find out.