USATSI

A pair of AFC South rivals led by rookie quarterbacks will square off on Sunday afternoon when the Houston Texans host the Indianapolis Colts. Texans quarterback C.J. Stroud was selected second in this year's draft and Colts quarterback Anthony Richardson was taken two picks later. Houston is coming off a 25-9 loss to Baltimore, while Indianapolis lost to Jacksonville in a 31-21 final. The Colts are 7-2-1 in their last 10 games against Houston.

Kickoff is scheduled for 1 p.m. ET at NRG Stadium. Houston is favored by 1 point in the latest Colts vs. Texans odds, and the over/under for total points scored is 39.5. Before making any Texans vs. Colts picks, you need to see the NFL predictions and betting advice from the computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the 2023 NFL season on an incredible 163-113 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 17-6 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Texans vs. Colts and just locked in its picks and NFL Week 2 predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for Colts vs. Texans:

  • Texans vs. Colts spread: Texans -1
  • Texans vs. Colts over/under: 39.5 points
  • Texans vs. Colts money line: Texans -115, Colts -104
  • Texans vs. Colts picks: See picks at SportsLine
  • Texans vs. Colts live stream: fubo (try for free)

Why the Texans can cover

Indianapolis has been struggling since the middle of last season, losing for the eighth straight time in its setback against Jacksonville last week. The Colts have only covered the spread once in their last seven games overall, and they are 1-5 in their last six road games. Houston has been profitable in recent games, covering the spread in four of its last six contests.

Stroud completed 28 of 44 passes for 242 yards last week, and Indianapolis is lacking firepower without running back Jonathan Taylor. The Colts managed just 65 rushing yards on 26 carries in their opener, averaging 2.5 yards per attempt. They were 2 of 12 on third-down attempts and 1 of 5 on fourth down, so they are too risky to back in a road environment. See which team to pick here.

Why the Colts can cover

The Colts fought hard against the Jaguars in their season opener, but in the end, their youth showed and they came up short. Rookie quarterback Anthony Richardson, who suffered a minor knee injury in Week 1, showed why he was a first-round pick, completing 24 of 37 pass attempts for 223 yards, one touchdown, and one interception. He also rushed for 40 yards and a TD. 

Defensively, the Colts held their own for most of the game against a Jaguars offense that is among the most talented in the league. Linebacker Zaire Franklin recorded 18 total tackles and defensive tackle DeForest Buckner notched seven tackles, one sack, one forced fumble, and scored a defensive touchdown. See which team to pick here.

How to make Colts vs. Texans picks

The model has simulated Texans vs. Colts 10,000 times and the results are in. It is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in 60% of simulations. You can only see the model's Colts vs. Texans pick at SportsLine.

So who wins Texans vs. Colts on Sunday, and which side of the spread is hitting 60% of the time? Visit SportsLine right now to see which side of the Texans vs. Colts spread you should be all over Sunday, all from the model on a 163-113 roll on its top-rated NFL picks, and find out.