The Cleveland Indians have been red hot since enduring a four-game losing streak in late April, winning 12 of 15 contests to climb within one game of first place in the American League Central. They have won eight of their last nine after overcoming a deficit on Wednesday and posting a 2-1 victory over the Chicago Cubs in 10 innings. Cleveland's chances for continued success appear good as it begins a four-game road series on Thursday against the Seattle Mariners, who have lost four in a row and seven of their last 10. Should you expect the Indians to post a fourth consecutive victory, or is there value in the Mariners to end their slide and bring a return on the money line?

The latest MLB odds for Thursday from WIlliam Hill Sportsbook list the Indians at -121 (risk $121 to win $100) against the Mariners. Other MLB lines of note include the San Francisco Giants at -153 against the Pittsburgh Pirates and the Boston Red Sox listed as slight money-line favorites (-111) versus the Oakland Athletics. Before making any MLB picks or predictions on those games or others, you need to see the MLB predictions and betting advice from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line MLB picks. It is off to a fast start in 2021, going 44-31 on top-rated MLB money-line picks through six weeks, returning more than $700. Anyone following it has seen huge rewards.

Now, the model has evaluated the latest MLB lines for Thursday and posted its best bets for the evening games. Parlaying these four MLB picks would pay almost 17-1. Head to SportsLine to see the picks

Top MLB picks for Thursday, May 13

The model likes the Athletics at +101 on the money line against the Red Sox. Boston has had trouble scoring runs of late, and as a result, its lead in the AL East has shrunk to one game. After scoring at least four runs in six straight contests (five wins), the Red Sox have produced a total of four while losing three in a row. Things won't get much easier for them on Thursday as they face Sean Manaea, who has given up fewer than three runs in five of his last six starts.

Over that span, the 29-year-old left-hander has posted a 3-0 record and 2.33 ERA with five walks and 39 strikeouts. He also has kept the ball in the park, serving up only two home runs over 36 ⅓ innings after allowing a pair of blasts over 4 ⅔ frames in his season debut. Manaea settled for a no-decision in his last outing despite limiting Tampa Bay to one run and two hits while fanning 10 batters over 7 ⅓ innings. 

How to make MLB predictions, parlays for Thursday, May 13

The model has locked in three other MLB best bets, including two on surprising underdogs. You can see the best bets only at SportsLine.

So which MLB picks should you make on Thursday for a shot at a big return close to 17-1? And which surprising underdog do you need to be all over? Visit SportsLine now to see Thursday's MLB picks, all from the projection model off to a fast start in 2021, and find out.