The New York Yankees (85-56) head over to Fenway Park to battle against the Boston Red Sox (69-72) on Tuesday evening in an MLB on TBS matchup. Both teams roll into this contest on two-game winning streaks. The Red Sox are 5-1 in their last six games following a win. Meanwhile, the Yankees are 6-2 in their last eight overall.

The first pitch is set for 7:10 p.m. ET from Boston. New York is listed as -160 favorites (risk $160 to win $100), while Boston is at +135 in the latest Yankees vs. Red Sox odds from Caesars Sportsbook. The over-under for total runs scored is 8.5. Before making any Yankees vs. Red Sox picks, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is a 316-272 on top-rated MLB money-line picks since the start of the 2021 season. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Yankees vs. Red Sox and revealed its coveted picks and predictions. You can head to SportsLine to see all of the model's MLB picks. Here are several MLB odds and trends for Red Sox vs. Yankees:

  • Yankees vs. Red Sox money line: Yankees -160, Red Sox +135
  • Yankees vs. Red Sox run-line: Boston +1.5 (-120)
  • Yankees vs. Red Sox over-under: 8.5 runs
  • NYY: Yankees are 6-2 in their last 8 overall
  • BOS: Red Sox are 4-0 in their last 4 home games
  • Yankees vs. Red Sox picks: See picks at SportsLine
Featured Game | Boston Red Sox vs. New York Yankees

Why you should back the Yankees

Designated hitter Giancarlo Stanton is a huge home-run threat for New York. Stanton has a big-time swing that can push the ball out of any ballpark with ease. The five-time All-Star brings a lot of juice to the lineup, and he has belted 26 home runs along with 68 RBI thus far. In his last outing, he went 1-for-2 with a three-run homer.

Second baseman Gleyber Torres is an athletic playmaker who is a reliable defender, has solid range and a strong arm. The 25-year-old can consistently make contact and get on base. He is batting .240 with 21 dingers, 58 RBI, and he's recorded two-plus hits in back-to-back games. 

Why you should back the Red Sox

Shortstop Xander Bogaerts is a phenomenal contact hitter for Boston. Bogaerts has great pitch recognition skills and bat control as the four-time All-Star is also a rangy defender with a smooth throwing arm. Bogaerts is fourth in the MLB in batting average (.319) with 13 dingers and 66 RBI. On Sept. 9, he went 3-for-5 with a two-run homer.

Third baseman Rafael Devers owns home-run power and run-producing abilities. The 25-year-old covers the plate well and forces opposing pitchers into high counts. Devers is currently hitting .290 with 26 home runs and 78 RBI. On Sept. 10, he was 3-for-5 with a grand slam.

How to make Yankees vs. Red Sox picks

SportsLine's model is leaning Over on the total, projecting 9.1 combined runs. It also says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Yankees vs. Red Sox? And which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.