The Golden State Warriors will take on the Philadelphia 76ers at 10 p.m. ET Wednesday at Chase Center. Golden State is 15-2 overall and 9-1 at home, while Philadelphia is 10-8 overall and 6-4 on the road. The Sixers have won two of their past three games, while the Warriors have won four consecutive.

The teams split their two meetings last season. Golden State is favored by 10.5 points in the latest Warriors vs. Sixers odds from Caesars Sportsbook, and the over-under is set at 217. Before entering any Sixers vs. Warriors picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $9,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model entered Week 6 of the 2021-22 NBA season up over $1,200 on all top-rated NBA picks this season. It's also on a stunning 115-76 roll on top-rated NBA picks against the spread that dates back to last season. Anyone following it has seen huge returns.

Now, the model has set its sights on Warriors vs. Sixers . You can head to SportsLine to see its picks. Here are several NBA betting lines for Warriors vs. 76ers:

  • Warriors vs. Sixers spread: Warriors -10.5
  • Warriors vs. Sixers over-under: 217 points
Featured Game | Golden State Warriors vs. Philadelphia 76ers

What you need to know about the Warriors

The Warriors rolled past the Raptors on Sunday, 119-104. Golden State is off to its best start in six seasons. Jordan Poole had 33 points, his second straight 30-point game. He made a career-best eight three-pointers on 11 attempts.

Andrew Wiggins scored 32 points on Sunday and made his first six three-point attempts. Golden State leads the NBA in scoring (114.2 points per game), assists (29.3 per game), opponent scoring (101.1 points per game), and opponent field goal percentage (.420). Andre Iguodala (hip) is out for Wednesday's game. 

What you need to know about the Sixers

The Sixers beat the Kings on Monday, 102-94. Philadelphia outscored Sacramento 25-12 in the fourth quarter. The Sixers are 6-0 when holding their opponents to under 100 points. Tyrese Maxey scored 24 points.

Andre Drummond had 23 rebounds on Monday, his third 20-rebound game of the season. Tobias Harris (hip), Seth Curry (back), and Danny Green (hamstring) are questionable for Wednesday's game. Joel Embiid (health and safety protocols) is out for the ninth consecutive game.   

How to make 76ers vs. Warriors picks

The model has simulated Warriors vs. 76ers 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Warriors vs. Sixers? And which side of the spread hits in over 50 percent of simulations? Visit SportsLine now to find out which side of the Sixers vs. Warriors spread you need to jump on Wednesday, all from the model that has crushed its NBA picks, and find out.