Teams off to solid starts to their seasons face off on Monday Night Football when the Philadelphia Eagles entertain the Minnesota Vikings. The Vikings (1-0), who have a new coach in Kevin O'Connell, stunned the defending NFC North champion Green Bay Packers last Sunday with a 23-7 win. The Eagles (1-0) got out to a big early lead and then held on for a 38-35 victory over the Detroit Lions. Both Philadelphia and Minnesota are coming off second-place finishes in their respective divisions.

Kickoff from Lincoln Financial Field in Philadelphia is set for 8:30 p.m. ET. Philadelphia is a 2.5-point favorite in the latest Vikings vs. Eagles odds from Caesars Sportsbook, while the over/under for total points scored is 49.5. Before making any Eagles vs. Vikings picks, be sure to see the NFL predictions and betting advice from SportsLine's Emory Hunt

Hunt is the founder and CEO of Football Gameplan, which has been supplying analysis of all levels of football since 2007. He is a former running back at Louisiana-Lafayette and knows the game from a player's perspective. In addition, Hunt has gone 35-20-1 on his last 56 NFL picks involving the Eagles, returning $1,281. Anyone who has followed him is way up.

Now, Hunt has set his sights on Eagles vs. Vikings and locked in his NFL picks and predictions. You can head to SportsLine to see his picks. Here are several NFL odds and trends for Vikings vs. Eagles:

  • Eagles vs. Vikings spread: Philadelphia -2.5
  • Eagles vs. Vikings over/under: 49.5 points
  • Eagles vs. Vikings money line: Minnesota +115, Philadelphia -135
  • MIN: Vikings are 4-1 against the spread in their last five September games
  • PHI: Eagles are 3-0-1 ATS in their last four games as home favorites
  • Eagles vs. Vikings picks: See picks at SportsLine
Featured Game | Philadelphia Eagles vs. Minnesota Vikings

Why the Eagles can cover

Quarterback Jalen Hurts was lethal against the Lions, passing for 243 yards and rushing for 90 more in Week 1. It was his fourth-career game with 75 or more rushing yards. Hurts had 15 touchdowns, eight rushing and seven passing, against two interceptions for a 92.7 rating in seven home starts in 2021. He passed for 326 yards and two touchdowns against two interceptions in his only career start on Monday Night Football, a 41-21 loss to the Dallas Cowboys on Sept. 27, 2021, at Dallas.

Running back Miles Sanders also had a solid opening week for the Eagles. Sanders had 105 yards from scrimmage, including 96 rushing and nine receiving, to go along with one rushing touchdown. It was his 10th career rushing TD. He has 1,616 scrimmage yards (85.1 per game) in 19 career home games and had 86 receiving yards and a touchdown catch in the last meeting against Minnesota.

Why the Vikings can cover

Wide receiver Justin Jefferson continues to impress. He had nine catches for a career-high 184 yards and two receiving touchdowns in Week 1 against the Packers. Jefferson has five career games with 150 or more receiving yards and a touchdown catch, which is tied for the second-most ever by a player in his first three career seasons. He has 182 receiving yards (91 per game) and a receiving touchdown in two career Monday Night Football games.

Defensively, safety Harrison Smith had a monster game against the Packers. Smith registered seven tackles, including five solo, and one pass breakup. He recorded his 30th career interception and is the only active player with 30 or more interceptions and 15 or more sacks (16.5). Smith will also be looking for his 11th road game in a row with five or more tackles.

How to make Eagles vs. Vikings picks

Hunt has analyzed this matchup from every angle and while we can tell you he's leaning Over the total, he has discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and who to back, at SportsLine.

So who wins Vikings vs. Eagles on Monday Night Football? And what critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the Vikings vs. Eagles spread to back, all from the NFL expert who's an amazing 35-20 on picks involving Philadelphia, and find out.