The Buffalo Bills will take on the Los Angeles Rams at 1 p.m. ET on Sunday at Bills Stadium. Both teams are 2-0. Buffalo is favored by 2.5 points in the latest Bills vs. Rams odds from William Hill, and the over-under is set at 47. Before entering any Rams vs. Bills picks, you'll want to see the NFL predictions from the model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up over $7,300 for $100 players on its top-rated NFL picks since its inception five-plus years ago. It's off to a strong 5-2 roll on top-rated NFL picks this season. The model enters Week 3 on an incredible 101-67 roll on top-rated NFL picks that dates back to the 2017 season.
The model also ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.
- Bills vs. Rams spread: Bills -2.5
- Bills vs. Rams over-under: 47 points
- Bills vs. Rams money line: Buffalo -140, Los Angeles +120
Why the Bills can cover
The Bills came out on top in a nail-biter against the Dolphins this past Sunday, 31-28. Josh Allen was on fire, passing for four TDs and 417 yards on 35 attempts. He set career standards in yardage and TD passes. Allen became the first Buffalo QB since 2002 with 400-plus passing yards in single game.
Stefon Diggs is tied for the NFL lead with 239 receiving yards. Devin Singletary has 110-plus scrimmage yards in three of his past games at home and he should take on a heavy workload this week with Zack Moss (toe) ruled out. Tre'Davious White has five passes defensed in his past three home games. Jordan Poyer had eight tackles and a sack vs. Miami.
Why the Rams can cover
The Rams didn't have too much trouble with the Philadelphia Eagles on the road this past Sunday as they won 37-19. Jared Goff threw all three of his TD passes to Tyler Higbee, who became the first Rams tight end since 1988 to register three scoring receptions in a game. Goff is one of four QBs with four games of three-plus TD passes and a rating of 140-plus since 2017. He had a 142.1 rating in Week 2.
Darrell Henderson had a career-high 121 scrimmage yards and a rushing TD in Week 2. Micah Kiser had a career-high 16 tackles and a forced fumble. Jordan Fuller is tied for second among rookies with 17 tackles after two games.
How to make Bills vs. Rams picks
SportsLine's model has simulated Bills vs. Rams 10,000 times and the results are in. The model is leaning under on the total, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.
So who wins Bills vs. Rams? And which side of the spread hits in over 50 percent of simulations? Visit SportsLine now to see which side of the Bills vs. Rams spread to jump on Sunday, all from the model that enters Week 3 of the NFL season on an incredible 101-67 roll.