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The Houston Texans and the Tennessee Titans will face off in an AFC South clash at 4:25 p.m. ET on Sunday at NRG Stadium. Houston is 4-11 overall and 2-5 at home, while Tennessee is 10-5 overall and 5-2 on the road. The Titans are the No. 4 seed in the AFC entering Week 17. The Titans won the first meeting of the season in Week 6, 42-36. 

Tennessee is favored by 7.5 points in the latest Texans vs. Titans odds from William Hill Sportsbook, and the over-under is set at 56. Before entering any Titans vs. Texans picks, you'll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception five-plus years ago. It is a sizzling 23-13 on top-rated NFL picks this season, returning well over $800. The model also enters Week 17 on an incredible 119-77 run on top-rated NFL picks that dates back to the 2017 season. 

The model ranked in the Top 10 on NFLPickWatch three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Texans vs. Titans. You can head to SportsLine to see its picks. Here are several NFL betting lines for Titans vs. Texans:

  • Texans vs. Titans spread: Texans +7.5
  • Texans vs. Titans over-under: 56 points
  • Texans vs. Titans money line: Houston +300 Tennessee 360

What you need to know about the Texans

Houston fell 37-31 to Cincinnati last week. It was the fourth consecutive loss for the Texans. Houston was driving for a potential tying score in the fourth quarter when Deshaun Watson lost a fumble. It was the third time in the past four games that the Texans have had a chance to win or tie a game late and lost a fumble. David Johnson rushed for 128 yards and a TD on 12 carries in addition to catching a TD pass. It was his first 100-yard rushing game of the season.

Watson completed 24 of 33 passes for 324 yards and three TDs vs. 0 INTs for a 133.9 rating last week. He is aiming for his fourth game in a row with 0 INTs and a 100-plus rating and third in a row with 315-plus pass yards and two-plus TD passes. He passed for 335 yards and four TDs vs. 0 INTs for a 138.9 rating in the Week 6 meeting with Tennessee. Watson has 16 TDs (14 passing) vs. four INTs for a 120.1 rating in five career games vs. the Titans. Brandin Cooks had nine catches for 68 yards and a TD in the Week 6 meeting.   

What you need to know about the Titans

Meanwhile, the Titans were demolished by the Green Bay Packers last week, 40-14. The Titans missed out on a chance to clinch the AFC South. They can still wrap up the division with a win over the Texans or with a Colts loss. Tennessee can clinch a playoff berth with losses by the Dolphins or Ravens. The Titans could miss the playoffs if they lose to the Texans and the Dolphins, Ravens and Colts win their games. The last time Tennessee won the division was 2008. 

The Titans allowed the Packers to score the game's first 19 points and last 21 points. The 14 points scored were the team's lowest output of the season. Ryan Tannehill was 11 of 24 for 121 yards with a pair of interceptions. Derrick Henry rushed for 98 yards on 23 carries, ending a streak of nine consecutive road games with 100 rushing yards. The Titans have allowed at least 27 points in each of their losses. Tennessee does have 54 offensive touchdowns, which is second in the NFL.

How to make Titans vs. Texans picks

The model has simulated Texans vs. Titans 10,000 times and the results are in. It is leaning under on the total, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Titans vs. Texans? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to see which side of the Titans vs. Texans spread to jump on Sunday, all from the model that enters Week 17 of the NFL season on an incredible 119-77 roll.