Conference championship games typically pit top teams against each other, but the latest college football odds indicate there could be several blowouts on tap Saturday. Ohio State vs. Wisconsin (+16.5) in the 2019 Big Ten Championship and Clemson vs. Virginia (+28.5) in the 2019 ACC Championship Game have the two largest college football spreads of the week, while Boise State vs. Hawaii (+14) in the 2019 Mountain West Championship is also projected to be a multi-score game.

Are any of those Championship Week college football lines too inflated, or will the heavy favorites roll? And which college football picks should you prioritize? Before making the call on those matchups or others, be sure to see the college football predictions from SportsLine's advanced computer model in order to make the best college football picks now.

The SportsLine Projection Model simulates every FBS college football game 10,000 times, and those who have followed it have seen huge returns. Over the past four-plus years, the proprietary computer model has generated a stunning profit of almost $4,000 for $100 players on its top-rated college football picks against the spread, helping bettors consistently beat college football odds. Now, it has turned its attention the college football schedule for Championship Week 2019. Head to SportsLine to see every pick.

One of the model's Championship Week college football predictions is that Miami (Ohio) stays within the spread as a 6.5-point underdog against Central Michigan in the 2019 MAC Championship Game.

The RedHawks opened the season at 2-4 thanks in large part to a brutal schedule that included games against Iowa, Cincinnati and Ohio State. After splitting their first two MAC games, they caught fire late in the season on their way to five wins in their last six games, including pivotal victories over MAC East challengers Kent State and Ohio. 

The RedHawks also went 4-2 against the spread in their final six games and have covered in 13 of their last 17 MAC games overall. Central Michigan was one of the best teams against the spread in the nation at 9-2, but SportsLine's model says the line is too large in this one. The RedHawks get 200 yards of passing from quarterback Brett Gabbert as they cover in 60 percent of simulations, while the under (55) also has plenty of value because that hits well over 60 percent of the time.

The model also has made the call against the spread, on the over-under, and on the money line for every other game on the Championship Week college football schedule, including the 2019 SEC Championship Game featuring LSU vs. Georgia as well as the Ohio State vs. Wisconsin matchup in the 2019 Big Ten Championship Game. It knows the line in one game is way off, saying one side of the spread hits in almost 60 percent of simulations. Get every pick for every game here. Now, here are the latest Championship Week college football odds:

So what college football picks can you make with confidence during Championship Week? And which line is way off? Check out the latest Championship Week college football odds above, and then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $4,000 in profit over the past four seasons.